| 3740_11 | |
| Organism | Mus musculus (mouse) |
| Function | Others |
| Cluster | 57 |
| Symbol | Trp53inp2 |
| Synonyms | 1110029F20Rik Tp53inp2 |
| Gene Name | transformation related protein 53 inducible nuclear protein 2 |
| Other Name | Trp53inp2 |
| Gene ID | 68728 |
| Nucleotide | NM_178111.3 XM_006500113.2 XM_006500114.2 |
| GI | 30017443 568918267 568918269 |
| Protein | NP_835212.1 XP_006500176.1 XP_006500177.1 |
| Genomic | AC_000024.1 NC_000068.7 NT_039207.8 NW_001030712.1 |
| UniProt | Q8CFU8 |
| Description | transformation related protein 53 inducible nuclear protein 2 |
| PDB Structure | - |
| Predicted Location | Cytoplasm, cytosol. Nucleus. Nucleus, PML body. Cytoplasmicvesicle, autophagosome. |
| Complex | - |
| Interaction | - |
| Interaction (Human) | - |
| VaProS | Q8CFU8 |
| Function (UniProt) | Dual regulator of transcription and autophagy. Positively regulates autophagy and is required for autophagosome formation and processing. May act as a scaffold protein that recruits MAP1LC3A, GABARAP and GABARAPL2 and brings them to the autophagosome membrane by interacting with VMP1 where, in cooperation with the BECN1-PI3-kinase class III complex, they trigger autophagosome development. Acts as a transcriptional activator of THRA. |
| UniGene | Mm.293605 Mm.474909 |
| Related Papers | 8889548 10349636 11042159 11076861 11217851 12466851 12477932 15489334 15782199 16141072 16141073 17238154 18725516 21467300 24713655 |
| Predicted Disordered Regions | [Dichot] |
| Sequence | >NP_835212.1 MFQRFTSLFFNTPAPPEDSNCPGAFVSEEDEVDGWLIIDLQDSYTAPPDPGASPAPAGRPPPAPSLMDESWFVTPPACFTAEGPGLGPARLQSNPLEDLLIEHPSMSVYVTGSTIVLESGPPSPHPEAALPDQDLSDGELAPALREPRALHHAAAPMPARAVLLEKAGQVRRLQRARQRAERHTLSAKVLQRQNRARESRSRRPKHQGSFIYQPCQRQFNY >XP_006500176.1 MFQRFTSLFFNTPAPPEDSNCPGAFVSEEDEVDGWLIIDLQDSYTAPPDPGASPAPAGRPPPAPSLMDESWFVTPPACFTAEGPGLGPARLQSNPLEDLLIEHPSMSVYVTGSTIVLESGPPSPHPEAALPDQDLSDGELAPALREPRALHHAAAPMPARAVLLEKAGQVRRLQRARQRAERHTLSAKVLQRQNRARESRSRRPKHQGSFIYQPCQRQFNY >XP_006500177.1 MFQRFTSLFFNTPAPPEDSNCPGAFVSEEDEVDGWLIIDLQEGPGLGPARLQSNPLEDLLIEHPSMSVYVTGSTIVLESGPPSPHPEAALPDQDLSDGELAPALREPRALHHAAAPMPARAVLLEKAGQVRRLQRARQRAERHTLSAKVLQRQNRARESRSRRPKHQGSFIYQPCQRQFNY |