| 55_4 | |
| Organism | Homo sapiens (human) |
| Function | Atg8 conjugation system |
| Cluster | 8 |
| Symbol | MAP1LC3A |
| Synonyms | ATG8E LC3 LC3A MAP1ALC3 MAP1BLC3 |
| Gene Name | microtubule-associated protein 1 light chain 3 alpha |
| Other Name | MAP1LC3A |
| Gene ID | 84557 |
| Nucleotide | NM_032514.3 NM_181509.2 XM_011529083.1 XM_011529084.1 XM_011529085.1 |
| GI | 14210522 31563518 768018500 768018504 768018507 |
| Protein | NP_115903.1 NP_852610.1 XP_011527385.1 XP_011527386.1 XP_011527387.1 |
| Genomic | NC_000020.11 NC_018931.2 NT_011362.11 NW_004929418.1 |
| UniProt | Q9H492 |
| Description | microtubule-associated protein 1 light chain 3 alpha |
| PDB Structure | 3ECI 3WAL 3WAN |
| Predicted Location | Cytoplasm, cytoskeleton. Endomembranesystem. |
| Complex | - |
| Interaction | [PPI (26)] |
| Interaction (Human) | - |
| VaProS | Q9H492 |
| Function (UniProt) | Ubiquitin-like modifier involved in formation of autophagosomal vacuoles (autophagosomes). Whereas LC3s are involved in elongation of the phagophore membrane, the GABARAP/GATE-16 subfamily is essential for a later stage in autophagosome maturation. |
| UniGene | Hs.632273 |
| Related Papers | 2212989 2470876 7908909 8833088 8997639 11076863 11096062 11230166 11278895 11780052 12477932 12740394 15187094 15213446 15342556 15383276 15489334 15489336 15857831 16169070 16286508 16303767 16341674 16381901 16704426 17102583 17438365 17580304 17804493 18448665 18653543 18688877 18695874 19021777 19056683 19250911 19322194 19427866 19492063 19549685 19623642 19696020 19812190 19820708 19838173 20004946 20010802 20010805 20023420 20061800 20153330 20168092 20204693 20352102 20382705 20398630 20417604 20479004 20495340 20505359 20529957 20562859 20639871 20713600 20937856 21045561 21048031 21262964 21316776 21412173 21415575 21460636 21497758 21507968 21537144 21556768 21617041 21628531 21674156 21684337 21709020 21729531 21812771 21832049 21845828 21909394 21935636 21943220 21988832 22011618 22237724 22249245 22267086 22281431 22328508 22354992 22411133 22421968 22505714 22647537 22648564 22714671 22728060 22963397 22974335 23043107 23089287 23209295 23219390 23239879 23333394 23345115 23376921 23434281 23449484 23459205 23602568 23624503 23632916 23681079 23752596 23787295 23956998 23989536 24023838 24067654 24070620 24100292 24186908 24282606 24290141 24404161 24440703 24528869 24532538 24619419 24690104 24886140 24899049 24998849 25005847 25026213 25042851 25132643 25136588 25147182 25339774 25384975 25416948 25416956 25466963 25490467 25498145 25601754 |
| Predicted Disordered Regions | [Dichot] |
| Sequence | >NP_115903.1 MPSDRPFKQRRSFADRCKEVQQIRDQHPSKIPVIIERYKGEKQLPVLDKTKFLVPDHVNMSELVKIIRRRLQLNPTQAFFLLVNQHSMVSVSTPIADIYEQEKDEDGFLYMVYASQETFGF >NP_852610.1 MKMRFFSSPCGKAAVDPADRCKEVQQIRDQHPSKIPVIIERYKGEKQLPVLDKTKFLVPDHVNMSELVKIIRRRLQLNPTQAFFLLVNQHSMVSVSTPIADIYEQEKDEDGFLYMVYASQETFGF >XP_011527385.1 MKMRFFSSPCGKAAVDPEMDLILSPRLECRAAITAHCSLELLGSSNSPVWAPQSAGITAAAAVLSASPGALEREARSPRSPQTADTSPRPRAPACAPSRARAMPSDRPFKQRRSFADRCKEVQQIRDQHPSKIPVIIERYKGEKQLPVLDKTKFLVPDHVNMSELVKIIRRRLQLNPTQAFFLLVNQHSMVSVSTPIADIYEQEKDEDGFLYMVYASQETFGF >XP_011527386.1 MKMRFFSSPCGKAAVDPEMDLILSPRLECRAAITAHCSLELLGSSNSPVWAPQSAGITAAAAVLSASPGALEREARSPRSPQTADTSPRPRAPACAPSRARAMPSDRPFKQRRSFADRCKEVQQIRDQHPSKIPVIIERYKGEKQLPVLDKTKFLVPDHVNMSELVKIIRRRLQLNPTQAFFLLVNQHSMVSVSTPIADIYEQEKDEDGFLYMVYASQETFGF >XP_011527387.1 MKMRFFSSPCGKAAVDPAAAAVLSASPGALEREARSPRSPQTADTSPRPRAPACAPSRARAMPSDRPFKQRRSFADRCKEVQQIRDQHPSKIPVIIERYKGEKQLPVLDKTKFLVPDHVNMSELVKIIRRRLQLNPTQAFFLLVNQHSMVSVSTPIADIYEQEKDEDGFLYMVYASQETFGF |