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Entry URI http://metadb.riken.jp/db/SciNetS_ria224i/cria224u4ria224u15728674i
Entry name Kirik Victor et al. 2005 Apr. Development 132(7):1477-85.
Title Functional diversification of MYB23 and GL1 genes in trichome morphogenesis and initiation.
Authors Herrmann Ullrich|Hulskamp Martin|Kirik Victor|Lee Myeong Min|Oppenheimer David|Schiefelbein John|Wester Katja|Zheng Zhengui
Abstract The functional diversification of duplicated genes is one of the driving forces in evolution. To understand the molecular mechanisms of gene diversification, we studied the functional relationship of the two Arabidopsis paralogous MYB-related genes GL1 and MYB23. We show that MYB23 controls trichome branching and trichome initiation at leaf edges. The latter is controlled redundantly together with GL1. We show that the two proteins are functionally equivalent during trichome initiation but not during trichome branching. RT-PCR and reporter construct analysis revealed spatial, temporal and genetic differences in transcriptional regulation of the GL1 and MYB23 genes. Presented data indicate that the diversification of GL1 and MYB23 gene functions occurred at the level of cis-regulatory sequences with respect to trichome initiation, and that, in parallel, the diversification with respect to regulation of trichome branching also involved changes in respective proteins.
Pubmed ID 15728674
Journal Development (Cambridge, England)
Volume 132
Issue 7
Pages 1477-85
Publication date 2005 Apr
Num of phenotype gene 2