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Entry URI http://metadb.riken.jp/db/SciNetS_ria224i/cria224u4ria224u12837952i
Entry name Mathur Jaideep et al. 2003 Jul. Plant Cell 15(7):1632-45.
Title Mutations in actin-related proteins 2 and 3 affect cell shape development in Arabidopsis.
Authors H端lskamp Martin|Kernebeck Birgit|Mathur Jaideep|Mathur Neeta
Abstract ACTIN-RELATED PROTEINS 2 and 3 form the major subunits of the ARP2/3 complex, which is known as an important regulator of actin organization in diverse organisms. Here, we report that two genes, WURM and DISTORTED1, which are important for cell shape control in Arabidopsis, encode the plant ARP2 and ARP3 orthologs, respectively. Mutations in these genes result in misdirected expansion of various cell types: trichome expansion is randomized, pavement cells fail to produce lobes, hypocotyl cells curl out of the normal epidermal plane, and root hairs are sinuous. At the subcellular level, cell shape changes are linked to severe filamentous actin aggregation and compromised vacuole fusion. Because all seven subunits of the ARP2/3 complex are present in plants, our data indicate that this complex may play a pivotal role during plant cell morphogenesis.
Pubmed ID 12837952
Journal The Plant cell
Volume 15
Issue 7
Pages 1632-45
Publication date 2003 Jul
Num of phenotype gene 6