132 | |
ID | 132 |
GRIP ID1 | 57 |
GRIP ID2 | 1 |
Template | 1l9hA |
Target | NP_000638.1 |
Interface | Val64 |
Template Start | 59 |
Template End | 59 |
Target Start | 64 |
Target End | 64 |
Annotation | It is possible for hetero dimerization, rather than homo dimerization, to occur between a mutant form of the CCR2 (the CCR2V64I), which helps to delay the development of AIDS in HIV-1-infected individuals, and the CCR5 or CXCR4, which are used by HIV to gain entry into cells. This result may explain why AIDS takes longer to develop in HIV-1-infected individuals carrying the CCR2V64I mutation. |
Article | 10466720 |