| 146 | |
| GRIP ID | 146 |
| Main Title | Information about hetero oligomer between CB1 cannabinoid receptor (CB1R) and opioid receptor ( OPR), and interfaces of OPR |
| GPCR Class | A |
| GPCR Subfamily | Cannabinoid |
| GPCR Subtype | CB1 |
| GPCR Name | CB1R |
| Partner Class | A |
| Partner Subfamily | Opioid |
| Partner Subtype | mu |
| Partner Name | muOPR |
| Evidence | Experiment |
| Annotations | muOPR-mediated signaling is attenuated by the CB1R agonist; this effect is reciprocal and is seen in heterologous cells and endogenous tissue expressing both receptors. Simultaneous activation of muOPR and CB1R leads to a significant attenuation of the response. |
| Articles | 16682964 |
| Methods | BRET, GTPgammaS binding and MAPK phosphorylation assays |
| Target | NP_057167.2 |
| Other Partners | - |
| Disease | - |
| Interface | - |
| Mutation Information | |
| Experimentaly Information | |
| Predicted Information | |