| 184 | |
| GRIP ID | 184 |
| Main Title | Information about homo oligomer of C5a complement component receptor (C5aR) and interfaces of C5aR |
| GPCR Class | A |
| GPCR Subfamily | Complement component |
| GPCR Subtype | C5a |
| GPCR Name | C5aR |
| Partner Class | A |
| Partner Subfamily | Complement component |
| Partner Subtype | C5a |
| Partner Name | C5aR |
| Evidence | Experiment |
| Annotations | Neither an intact NH2 terminus nor the presence of COOH-terminal phosphorylation sites appeared to be required for the formation of C5aR dimers.Upon C5a stimulation, mutant receptors did not internalize when individually expressed. C5a stimulation of cells that co-expressed wild type C5aR together with either unliganded or phosphorylation-deficient mutant resulted in co-internalization of mutant receptors with C5aR. |
| Articles | 18772131 |
| Methods | NH2-terminally modified C5aR mutant |
| Target | NP_001727.1 |
| Other Partners | - |
| Disease | - |
| Interface | - |
| Mutation Information | |
| Experimentaly Information | |
| Predicted Information | |