| 80 | |
| GRIP ID | 80 |
| Main Title | Information about homo oligomer of melanocortin type 1 receptor (MC1R) and interfaces of MC1R |
| GPCR Class | A |
| GPCR Subfamily | Melanocortin |
| GPCR Subtype | Type1 |
| GPCR Name | MC1R |
| Partner Class | A |
| Partner Subfamily | Melanocortin |
| Partner Subtype | Type1 |
| Partner Name | MC1R |
| Evidence | Experiment |
| Annotations | Three dimers, consisting of a ligand region, a short, flexible, uncharged spacer, a longer, polylysine spacer and a single cysteine residue to permit dimerization, and the corresponding monomers were characterized in a functional melanocyte dispersion assay. Peptide dimers have enhanced functional activity; monospecific dimers have greater avidity and bispecific dimers are likely to have greater selectivity. |
| Articles | 8807885 |
| Methods | Ligand binding assay by using bivalent peptide ligands |
| Target | NP_002377.4 |
| Other Partners | - |
| Disease | - |
| Interface | - |
| Mutation Information | |
| Experimentaly Information | |
| Predicted Information | |