| 83 | |
| GRIP ID | 83 |
| Main Title | Information about hetero oligomer between melatonin 1B and 1A receptors (MLT1BR - MLT1AR) and interfaces of MLT1BR |
| GPCR Class | A |
| GPCR Subfamily | Melatonin |
| GPCR Subtype | MLT1B |
| GPCR Name | MLT1BR |
| Partner Class | A |
| Partner Subfamily | Melatonin |
| Partner Subtype | MLT1A |
| Partner Name | MLT1AR |
| Evidence | Experiment |
| Annotations | Hetero dimers between MT1AR and MT1BR are the predominant receptor species, and this oligomerization state does not change upon agonist and antagonist binding. Agonists, neutral antagonists, and inverse agonists increase BRET values for MT1BR but not for MT1AR homodimers in living cells and isolated plasma membranes. |
| Articles | 11940583 |
| Methods | Immunoprecipitation, BRET |
| Target | NP_005950.1 |
| Other Partners | - |
| Disease | - |
| Interface | - |
| Mutation Information | |
| Experimentaly Information | |
| Predicted Information | |