| H00279 | |
| H number | H00279 |
| Name | Uropathogenic Escherichia coli (UPEC) infection |
| Description | Uropathogenic Escherichia coli (UPEC) infection is a prevalent infectious disease with potentially severe complications. UPEC, the most common etiological agent of community-acquired urinary tract infections (UTIs), accounts for >80% of UTI infections worldwide. Once inside the urinary tract, UPEC preferentially colonizes the bladder and causes cystitis, but can also ascend through the ureters into the kidneys, causing pyelonephritis. |
| Category | Bacterial infectious disease |
| Network | - |
| Gene | - |
| Pathogen | Escherichia coli (UPEC) [GN:ecp ena ecos eum ect eci ecc ecoj] pore-forming toxin [KO:K11003 K11004 K11005] |
| Env factor | - |
| Carcinogen | - |
| Drug | - |
| Comment | - |
| Other DBs | ICD-11: GC08.0 ICD-10: N39 MeSH: D004927 |
| Reference | PMID:9551528 AUTHORS Matsumoto T TITLE [Virulence factors and host responses in urinary tract infections]. JOURNAL J UOEH 20:45-60 (1998) DOI:10.7888/juoeh.20.45 PMID:16100859 AUTHORS Mehnert-Kay SA TITLE Diagnosis and management of uncomplicated urinary tract infections. JOURNAL Am Fam Physician 72:451-6 (2005) PMID:16406777 AUTHORS Svanborg C, Bergsten G, Fischer H, Godaly G, Gustafsson M, Karpman D, Lundstedt AC, Ragnarsdottir B, Svensson M, Wullt B TITLE Uropathogenic Escherichia coli as a model of host-parasite interaction. JOURNAL Curr Opin Microbiol 9:33-9 (2006) DOI:10.1016/j.mib.2005.12.012 PMID:17458672 AUTHORS Yamamoto S TITLE Molecular epidemiology of uropathogenic Escherichia coli. JOURNAL J Infect Chemother 13:68-73 (2007) DOI:10.1007/s10156-007-0506-y PMID:18482721 AUTHORS Wiles TJ, Kulesus RR, Mulvey MA TITLE Origins and virulence mechanisms of uropathogenic Escherichia coli. JOURNAL Exp Mol Pathol 85:11-9 (2008) DOI:10.1016/j.yexmp.2008.03.007 PMID:18616559 AUTHORS Dhakal BK, Kulesus RR, Mulvey MA TITLE Mechanisms and consequences of bladder cell invasion by uropathogenic Escherichia coli. JOURNAL Eur J Clin Invest 38 Suppl 2:2-11 (2008) DOI:10.1111/j.1365-2362.2008.01986.x |