| H00304 | |
| H number | H00304 |
| Name | Haemophilus influenzae infection |
| Description | Haemophilus influenzae type b (Hib) infections are a major cause of severe infections in children between 2 months and 5 years of age worldwide. It affects approximately 25000 patients each year. Severity of the symptoms of Hib infection depends on the patient's age, and infants between 4 months and 1 year of age are at highest risk for meningitis. Invasive disease due to Hib may produce various clinical syndromes including meningitis, arthritis, pneumonia, cellulitis, osteomyelitis, and epiglottitis. Mucosal infections, such as bronchitis, sinusitis and conjunctivitis, and otitis media, can also be caused by Hib, but they are considered to be noninvasive disease. |
| Category | Bacterial infectious disease |
| Network | - |
| Gene | - |
| Pathogen | Haemophilus influenzae [GN:hin hit hip hiq hiu hik hih] |
| Env factor | - |
| Carcinogen | - |
| Drug | - |
| Comment | American Indians and Alaskan Eskimos are at increased risk specifically for meningitis caused by Hib. |
| Other DBs | ICD-11: 1D01.00 CA40.02 CA42.4 ICD-10: A41.3 A49.2 G00.0 J14 J20.1 MeSH: D006192 |
| Reference | PMID:2194406 AUTHORS Janai H, Stutman HR, Marks MI TITLE Invasive Haemophilus influenzae type B infections: a continuing challenge. JOURNAL Am J Infect Control 18:160-6 (1990) DOI:10.1016/0196-6553(90)90181-Q PMID:22244051 AUTHORS Ladhani SN TITLE Two decades of experience with the Haemophilus influenzae serotype b conjugate vaccine in the United Kingdom. JOURNAL Clin Ther 34:385-99 (2012) DOI:10.1016/j.clinthera.2011.11.027 PMID:20980793 AUTHORS Fitzwater SP, Watt JP, Levine OS, Santosham M TITLE Haemophilus influenzae type b conjugate vaccines: considerations for vaccination schedules and implications for developing countries. JOURNAL Hum Vaccin 6:810-8 (2010) DOI:10.4161/hv.6.10.13017 PMID:3325012 AUTHORS Gilbert GL TITLE Epidemiology and prevention of invasive Haemophilus influenzae type b infection. JOURNAL Aust Paediatr J 23:323-7 (1987) DOI:10.1111/j.1440-1754.1987.tb00283.x |