| H00323 | |
| H number | H00323 |
| Name | Spotted fever; Tick-borne rickettsioses |
| Description | Tick-borne rickettsioses are caused by gram-negative obligate intracellular bacteria belonging to the spotted fever group (SFG) of the genus Rickettsia within the family Rickettsiaceae in the order Rickettsiales. The diseases present with high fever, an inoculation eschar, and a maculopapular rash. |
| Category | Bacterial infectious disease |
| Network | - |
| Gene | - |
| Pathogen | Rickettsia rickettsii [GN:rri] (Rocky Mountain spotted fever) Rickettsia conorii [GN:rco] (African tick typhus / Boutonneuse fever) Rickettsia felis [GN:rfe] (flea-borne spotted fever) Rickettsia sibirica (North Asian tick fever / Siberian tick typhus) Rickettsia massiliae [GN:rms] Rickettsia africae [GN:raf] Rickettsia japonica [GN:rja] (Japanese spotted fever) Rickettsia heilongjiangensis [GN:rhe] (Far-Eastern spotted fever) |
| Env factor | - |
| Carcinogen | - |
| Drug | Tetracycline hydrochloride [DR:D02122] Doxycycline [DR:D00307] Doxycycline hyclate [DR:D02129] Doxycycline calcium [DR:D03903] Minocycline hydrochloride [DR:D00850] Demeclocycline hydrochloride [DR:D00290] |
| Comment | Vectors: Rhipicephalus sanguineus (brown dog tick) for Rickettsia conorii |
| Other DBs | ICD-11: 1C31 ICD-10: A77 MeSH: D012373 D001907 MedlinePlus: 000654 |
| Reference | PMID:16223955 AUTHORS Parola P, Paddock CD, Raoult D TITLE Tick-borne rickettsioses around the world: emerging diseases challenging old concepts. JOURNAL Clin Microbiol Rev 18:719-56 (2005) DOI:10.1128/CMR.18.4.719-756.2005 PMID:19358804 AUTHORS Socolovschi C, Mediannikov O, Raoult D, Parola P TITLE The relationship between spotted fever group Rickettsiae and ixodid ticks. JOURNAL Vet Res 40:34 (2009) DOI:10.1051/vetres/2009017 PMID:15225980 AUTHORS Parola P TITLE Tick-borne rickettsial diseases: emerging risks in Europe. JOURNAL Comp Immunol Microbiol Infect Dis 27:297-304 (2004) DOI:10.1016/j.cimid.2004.03.006 PMID:18755389 AUTHORS Cazorla C, Socolovschi C, Jensenius M, Parola P TITLE Tick-borne diseases: tick-borne spotted fever rickettsioses in Africa. JOURNAL Infect Dis Clin North Am 22:531-44, ix-x (2008) DOI:10.1016/j.idc.2008.03.009 |