| H00356 | |
| H number | H00356 |
| Name | Cryptosporidiosis |
| Description | Human cryptosporidiosis is a self-limited diarrheal disease characterized by acute, persistent, or chronic diarrhea and biliary/pulmonary disease. Transmission of the causative agent, Cryptosporidium, occurs by the fecal-oral route. Water-borne transmission often occurs. The disease can be potentially serious in immunocompromised patients. |
| Category | Parasitic infectious disease |
| Network | - |
| Gene | - |
| Pathogen | Cryptosporidium parvum [GN:cpv] Cryptosporidium hominis [GN:cho] |
| Env factor | - |
| Carcinogen | - |
| Drug | Nitazoxanide [DR:D02486] |
| Comment | The most important therapy is hydroelectrolytic resuscitation. Antiretroviral therapy appears to play a critical role in resolution of AIDS-associated cryptosporidiosis. |
| Other DBs | ICD-11: 1A32 ICD-10: A07.2 MeSH: D003457 MedlinePlus: 000617 |
| Reference | PMID:20521158 AUTHORS Collinet-Adler S, Ward HD TITLE Cryptosporidiosis: environmental, therapeutic, and preventive challenges. JOURNAL Eur J Clin Microbiol Infect Dis 29:927-35 (2010) DOI:10.1007/s10096-010-0960-9 PMID:12686887 AUTHORS Chappell CL, Okhuysen PC TITLE Cryptosporidiosis. JOURNAL Curr Opin Infect Dis 15:523-7 (2002) DOI:10.1097/00001432-200210000-00012 PMID:20689422 AUTHORS Cabada MM, White AC Jr TITLE Treatment of cryptosporidiosis: do we know what we think we know? JOURNAL Curr Opin Infect Dis 23:494-9 (2010) DOI:10.1097/QCO.0b013e32833de052 PMID:22029525 AUTHORS McDonald V TITLE Cryptosporidiosis: host immune responses and the prospects for effective immunotherapies. JOURNAL Expert Rev Anti Infect Ther 9:1077-86 (2011) DOI:10.1586/eri.11.123 |