H01062 | |
H number | H01062 |
Name | Histoplasmosis |
Description | Histoplasmosis is a disease caused by the fungus Histoplasma capsulatum that occurs in temperate and tropical climates. It is one of the most frequent invasive fungal infections in immunocompromised patients or patients receiving tumor necrosis factor (TNF) blockers. Most affected patients present with pneumonitis, and sometimes the disease may be disseminated from the lungs to other organs. |
Category | Fungal infectious disease |
Network | - |
Gene | - |
Pathogen | Histoplasma capsulatum [GN:aje] Tumor necrosis factor (TNF) blockers [DR:D02598 D02597 D00742] |
Env factor | - |
Carcinogen | - |
Drug | Amphotericin B [DR:D00203] Ketoconazole [DR:D00351] Itraconazole [DR:D00350] |
Comment | - |
Other DBs | ICD-11: 1F2A ICD-10: B39.9 MeSH: D006660 |
Reference | PMID:22025021 AUTHORS Gupta AO, Singh N TITLE Immune reconstitution syndrome and fungal infections. JOURNAL Curr Opin Infect Dis 24:527-33 (2011) DOI:10.1097/QCO.0b013e32834ab20a PMID:22196208 AUTHORS Perfect JR TITLE The impact of the host on fungal infections. JOURNAL Am J Med 125:S39-51 (2012) DOI:10.1016/j.amjmed.2011.10.010 PMID:19951231 AUTHORS Hage CA, Bowyer S, Tarvin SE, Helper D, Kleiman MB, Joseph Wheat L TITLE Recognition, diagnosis, and treatment of histoplasmosis complicating tumor necrosis factor blocker therapy. JOURNAL Clin Infect Dis 50:85-92 (2010) DOI:10.1086/648724 PMID:19843232 AUTHORS Jazwinski A, Naggie S, Perfect J TITLE Immune reconstitution syndrome in a patient with disseminated histoplasmosis and steroid taper: maintaining the perfect balance. JOURNAL Mycoses 54:270-2 (2011) DOI:10.1111/j.1439-0507.2009.01796.x PMID:17409220 AUTHORS LeMonte A, Egan L, Connolly P, Durkin M, Wheat LJ TITLE Evaluation of the IMMY ALPHA Histoplasma antigen enzyme immunoassay for diagnosis of histoplasmosis marked by antigenuria. JOURNAL Clin Vaccine Immunol 14:802-3 (2007) DOI:10.1128/CVI.00035-07 |