H01362 | |
H number | H01362 |
Name | Dermatitis herpetiformis |
Description | Dermatitis herpetiformis (DH) is a chronic, polymorphic, pruritic skin disease that develops mostly in patients with latent gluten-sensitive enteropathy. There is an association with the genotypes HLA DR3, HLA DQw2, found in 80-90% of cases. Owing to the granular immunoglobulin (Ig) A deposition at the tips of the papillary dermis and to the subepidermal blister formation associated with neutrophilic accumulations underlying the basement membrane, DH is considered to be an autoimmune blistering disease. |
Category | Immune system disease; Skin disease |
Network | - |
Gene | HLA-DQA1 [HSA:3117] [KO:K06752] HLA-DQB1 [HSA:3119] [KO:K06752] HLA-DR3 HLA-B8 |
Pathogen | - |
Env factor | - |
Carcinogen | - |
Drug | Triamcinolone acetonide [DR:D00983] Dexamethasone [DR:D00292] Hydrocortisone sodium succinate [DR:D00978] Prednisolone [DR:D00472] Prednisolone sodium phosphate [DR:D00981] Prednisone [DR:D00473] Methylprednisolone [DR:D00407] Methylprednisolone sodium succinate [DR:D00751] Methylprednisolone acetate [DR:D00979] Dapsone [DR:D00592] Cortisone acetate [DR:D00973] |
Comment | - |
Other DBs | ICD-11: EB44 ICD-10: L13.0 |
Reference | PMID:22811741 AUTHORS Nakajima K TITLE Recent advances in dermatitis herpetiformis. JOURNAL Clin Dev Immunol 2012:914162 (2012) DOI:10.1155/2012/914162 PMID:24068131 AUTHORS Mendes FB, Hissa-Elian A, de Abreu MA, Goncalves VS TITLE Review: dermatitis herpetiformis. JOURNAL An Bras Dermatol 88:594-9 (2013) DOI:10.1590/abd1806-4841.20131775 PMID:22137227 AUTHORS Karpati S TITLE Dermatitis herpetiformis. JOURNAL Clin Dermatol 30:56-9 (2012) DOI:10.1016/j.clindermatol.2011.03.010 PMID:21571168 AUTHORS Bolotin D, Petronic-Rosic V TITLE Dermatitis herpetiformis. Part II. Diagnosis, management, and prognosis. JOURNAL J Am Acad Dermatol 64:1027-33; quiz 1033-4 (2011) DOI:10.1016/j.jaad.2010.09.776 PMID:23674144 AUTHORS Plotnikova N, Miller JL TITLE Dermatitis herpetiformis. JOURNAL Skin Therapy Lett 18:1-3 (2013) PMID:19470076 AUTHORS Caproni M, Antiga E, Melani L, Fabbri P TITLE Guidelines for the diagnosis and treatment of dermatitis herpetiformis. JOURNAL J Eur Acad Dermatol Venereol 23:633-8 (2009) DOI:10.1111/j.1468-3083.2009.03188.x |