| 1U22 | |
| PDB ID | 1U22 |
| Japanese name | シロイヌナズナ |
| English name | Arabidopsis |
| Scientific name | Arabidopsis thaliana (L.) Heynh. |
| Protein name | 5-Methyltetrahydropteroyltriglutamate--Homocysteine Methyltransferase De |
| Gene name | Name=Cims; Orderedlocusnames=At5g17920; Orfnames=Mpi7.9; |
| Source/Organism | Arabidopsis Thaliana |
| Compound | Molecule: 5-Methyltetrahydropteroyltriglutamate-- Homocysteine Methyltransferase; Chain: A; Synonym: Vitamin-B12-Independent Methionine Synthase Isozyme, Cobalamin-Independent Methionine Synthase Isozyme; Engineered: Yes |
| Classification | Transferase |
| EC number | 2.1.1.14 (5-Methyltetrahydropteroyltriglutamate-- ) |
| Authors | J.-L.Ferrer, S.Ravanel, M.Robert, R.Dumas |
| Reference | J.-L.Ferrer, S.Ravanel, M.Robert, R.Dumas Crystal Structures Of Cobalamin-Independent Methion Synthase Complexed With Zn, Homocysteine And Methyltetrahydrofolate J.Biol.Chem 2004 |
| Key word | Methionine,Synthase,Homocysteine,Methyltetrahydrofolate |
| Cross reference | SWS:METE_ARATH,O50008 EMBL; U97200; AAC50037.1; -. EMBL; AB011480; BAB11226.1; -. EMBL; AF370522; AAK43899.1; -. SWISS-2DPAGE; O50008; ARATH. InterPro; IPR002629; Methionine_synth. InterPro; IPR006276; Mtfrase_B12ind. Pfam; PF01717; Methionine_synt; 1. ProDom; PD004692; Methionine_synth; 1. TIGRFAMs; TIGR01371; met_syn_B12ind; 1. |
| Experimental method | X-Ray Diffraction, Resolution: 2.65 Angstrom, R-Factor: 0.200, R-Free: 0.270 |
| Sequence characteristics | Length: 765 AA, Molecular weight: 84356 Da |
| Sequence | MASHIVGYPRMGPKRELKFALESFWDGKSTAEDLQKVSADLRSSIWKQMSAAGTKFIPSN TFAHYDQVLDTTAMLGAVPPRYGYTGGEIGLDVYFSMARGNASVPAMEMTKWFDTNYHYI VPELGPEVNFSYASHKAVNEYKEAKALGVDTVPVLVGPVSYLLLSKAAKGVDKSFELLSL LPKILPIYKEVITELKAAGATWIQLDEPVLVMDLEGQKLQAFTGAYAELESTLSGLNVLV ETYFADIPAEAYKTLTSLKGVTAFGFDLVRGTKTLDLVKAGFPEGKYLFAGVVDGRNIWA NDFAASLSTLQALEGIVGKDKLVVSTSCSLLHTAVDLINETKLDDEIKSWLAFAAQKVVE VNALAKALAGQKDEALFSANAAALASRRSSPRVTNEGVQKAAAALKGSDHRRATNVSARL DAQQKKLNLPILPTTTIGSFPQTVELRRVRREYKAKKVSEEDYVKAIKEEIKKVVDLQEE LDIDVLVHGEPERNDMVEYFGEQLSGFAFTANGWVQSYGSRCVKPPVIYGDVSRPKAMTV FWSAMAQSMTSRPMKGMLTGPVTILNWSFVRNDQPRHETCYQIALAIKDEVEDLEKGGIG VIQIDEAALREGLPLRKSEHAFYLDWAVHSFRITNCGVQDSTQIHTHMCYSHFNDIIHSI IDMDADVITIENSRSDEKLLSVFREGVKYGAGIGPGVYDIHSPRIPSSEEIADRVNKMLA VLEQNILWVNPDCGLKTRKYTEVKPALKNMVDAAKLIRSQLASAK |
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