| 1HU9 | |
| PDB ID | 1HU9 |
| Japanese name | 大豆 |
| English name | Soybean |
| Scientific name | Glycine max (L.) Merrill |
| Protein name | Seed Lipoxygenase-3 |
| Gene name | Name=Lox1.3; Synonyms=Lox3; |
| Source/Organism | Glycine Max |
| Compound | Molecule: Lipoxygenase-3; Chain: A; Synonym: L-3; Other_details: Complex With 4-Hydroperoxy-2-Methoxy-Phenol A Photodegredation Product Of Curcumin |
| Classification | Oxidoreductase |
| EC number | 1.13.11.12 (Lipoxygenase-3) |
| Authors | K.Zhou, E.Skrzypczak-Jankun, N.P.Mccabe, S.H.Selman, J.Jankun |
| Reference | E.Skrzypczak-Jankun, K.Zhou, N.P.Mccabe, S.H.Selman, J.Jankun Structure Of Curcumin In Complex With Lipoxygenase And Its Significance In Cancer. Int.J.Mol.Med. V. 12 17 2003 |
| Key word | Oxidoreductase, Metalloprotein, Fe(Iii) Complex, Purple Lipoxygenase, Enzyme Inhibitor |
| Cross reference | SWS:LOX3_SOYBN,P09186 EMBL; X06928; CAA30016.1; -. EMBL; X13302; CAA31664.1; ALT_SEQ. EMBL; U50081; AAB41272.1; -. PDB; 1HU9; X-ray; A=1-857. PDB; 1IK3; X-ray; A=1-857. PDB; 1JNQ; X-ray; A=1-857. PDB; 1LNH; X-ray; @=1-857. PDB; 1N8Q; X-ray; A=1-857. PDB; 1NO3; X-ray; A=1-857. InterPro; IPR000907; Lipoxygenase. InterPro; IPR001024; Lipoxygenase_LH2. InterPro; IPR001246; Plant_lipoxygnse. InterPro; IPR008976; PLAT_LH2. Pfam; PF00305; Lipoxygenase; 1. Pfam; PF01477; PLAT; 1. PRINTS; PR00087; LIPOXYGENASE. PRINTS; PR00468; PLTLPOXGNASE. SMART; SM00308; LH2; 1. PROSITE; PS00711; LIPOXYGENASE_1; 1. PROSITE; PS00081; LIPOXYGENASE_2; 1. PROSITE; PS50095; PLAT; 1. |
| Experimental method | X-Ray Diffraction, Resolution: 2.20 Angstrom, R-Factor: 0.185, R-Free: 0.271 |
| Sequence characteristics | Length: 857 AA, Molecular weight: 96758 Da |
| Sequence | MLGGLLHRGHKIKGTVVLMRKNVLHVNSVTSVGGIIGQGLDLVGSTLDTLTAFLGRPVSL QLISATKADANGKGKLGKATFLEGIITSLPTLGAGQSAFKINFEWDDGSGILGAFYIKNF MQTEFFLVSLTLEDIPNHGSIHFVCNSWIYNAKLFKSDRIFFANQTYLPSETPAPLVKYR EEELHNLRGDGTGERKEWERVYDYDVYNDLGDPDKGENHARPVLGGNDTFPYPRRGRTGR KPTRKDPNSESRSNDVYLPRDEAFGHLKSSDFLTYGLKSVSQNVLPLLQSAFDLNFTPRE FDSFDEVHGLYSGGIKLPTDIISKISPLPVLKEIFRTDGEQALKFPPPKVIQVSKSAWMT DEEFAREMLAGVNPNLIRCLKEFPPRSKLDSQVYGDHTSQITKEHLEPNLEGLTVDEAIQ NKRLFLLGHHDPIMPYLRRINATSTKAYATRTILFLKNDGTLRPLAIELSLPHPQGDQSG AFSQVFLPADEGVESSIWLLAKAYVVVNDSCYHQLVSHWLNTHAVVEPFIIATNRHLSVV HPIYKLLHPHYRDTMNINGLARLSLVNDGGVIEQTFLWGRYSVEMSAVVYKDWVFTDQAL PADLIKRGMAIEDPSCPHGIRLVIEDYPYAVDGLEIWDAIKTWVHEYVFLYYKSDDTLRE DPELQACWKELVEVGHGDKKNEPWWPKMQTREELVEACAIIIWTASALHAAVNFGQYPYG GLILNRPTLSRRFMPEKGSAEYEELRKNPQKAYLKTITPKFQTLIDLSVIEILSRHASDE VYLGERDNPNWTSDTRALEAFKRFGNKLAQIENKLSERNNDEKLRNRCGPVQMPYTLLLP SSKEGLTFRGIPNSISI |
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