| SKIP001132 | |
| SKIP ID | SKIP001132 |
| Organism(En) | - |
| Organism(Ja) | - |
| Cell Type(En) | - |
| Cell Type(Ja) | - |
| Cell Tissue(En) | - |
| Cell Tissue(Ja) | - |
| Cell Origin | Diseased |
| Cell Name 1(En) | hiPS-RP#5 |
| Cell Name 1(Ja) | hiPS-RP#5 |
| Cell Name 2(En) | - |
| Cell Name 2(Ja) | - |
| Disease Name 1(Ja) | 網膜色素変性症 |
| ICD Code 1 | H35.5 |
| Disease Name 1(En) | retinitis pigmentosa |
| OMIM1 | - |
| Disease Name 2(Ja) | - |
| ICD Code 2 | - |
| Disease Name 2(En) | - |
| OMIM 2 | - |
| Disease Name 3(Ja) | - |
| ICD Code 3 | - |
| Disease Name 3(En) | - |
| OMIM 3 | - |
| Age | - |
| Age Range | -- |
| Sex | Female |
| Race(En) | - |
| Race(Ja) | - |
| Genetic Diagnosis | Yes |
| Not Detected | No |
| Description(En) | It was made from fibroblast cells from patient skin by introducing yamanaka 4 factors by retrovirus. |
| Description(Ja) | 網膜色素変性症患者繊維芽細胞由来iPS細胞。 |
| Cell Morphology | human ES-like |
| Grade | Research Grade |
| Vector | Retrovirus |
| Transgene | OCT4,SOX2,KLF4,C-MYC |
| Adhesiveness | - |
| Feeder | Yes |
| Feeder Cell | MEF |
| Medium | - |
| Genome Editing | - |
| CO2 | - |
| Mycoplasma | - |
| Detection of Contaminants Mycoplasma | - |
| Pluripotent Markers | Yes |
| Pluripotent Markers Assay | Immunostaining |
| in vitro Differentiation | - |
| in vitro Differentiation Assay | - |
| in vivo Differentiation | Yes |
| in vivo Differentiation Assay | Teratoma formation |
| Other 1 Assay | Yes |
| Other 1 Assay Method | Differentiation of rod photoreceptor cells |
| Other 2 Assay | - |
| Other 2 Assay Method | - |
| Other 3 Assay | - |
| Other 3 Assay Method | - |
| Karyotype | - |
| Karyotype Assay | - |
| Remaining Vector Detection | - |
| Remaining Vector Detection Assay | - |
| STR | - |
| HLA | - |
| Stem Cell Transcriptome analysis | - |
| Stem Cell Transcriptome analysis Assay | - |
| Author Name(En) | Yoko Ozawa |
| Author Name(Ja) | 小沢洋子 |
| Author Organization(En) | Laboratory of Retinal Cell Biology, Department of Ophthalmology, Keio University School of Medicine |
| Author Organization(Ja) | 慶應義塾大学医学部眼科学教室網膜細胞生物学研究室 |
| Author Contact Email | ozawa[at]a5[dot]keio[dot]jp |
| PI Organization(En) | Laboratory of Retinal Cell Biology, Department of Ophthalmology, Keio University School of Medicine |
| PI Organization(Ja) | 慶應義塾大学医学部眼科学教室網膜細胞生物学研究室 |
| PI Name(En) | Yoko Ozawa |
| PI Name(Ja) | 小沢洋子 |
| PI Contact Email | ozawa[at]a5[dot]keio[dot]jp |
| Availability | Available |
| Provider Organization(En) | Laboratory of Retinal Cell Biology, Department of Ophthalmology, Keio University School of Medicine |
| Provider Organization(Ja) | 慶應義塾大学医学部眼科学教室網膜細胞生物学研究室 |
| Provider Email | ozawa[at]a5[dot]keio[dot]jp |
| Provider URL | http://www.keio-eye.net/ |
| Ethical Statement(En) | - |
| Ethical Statement(Ja) | - |
| Terms of Use(En) | - |
| Terms of Use(Ja) | - |
| PubMed ID | 24935155 |
| DOI | 10.1186/1756-6606-7-45 |
| Title | The use of induced pluripotent stem cells to reveal pathogenic gene mutations and explore treatments for retinitis pigmentosa. |
| Authors | Yoshida T, Ozawa Y, Suzuki K, Yuki K, Ohyama M, Akamatsu W, Matsuzaki Y, Shimmura S, Mitani K, Tsubota K, Okano H |
| Journal | Mol Brain |
| Year | 2014 |
| Volume | 7 |
| Issue | - |
| Pages | 45 |
| URL | http://www.ncbi.nlm.nih.gov/pubmed/24935155 |
| Free input | - |
| Note | - |