SKIP000913 |
SKIP ID |
SKIP000913 |
Organism(En) |
- |
Organism(Ja) |
- |
Cell Type(En) |
- |
Cell Type(Ja) |
- |
Cell Tissue(En) |
- |
Cell Tissue(Ja) |
- |
Cell Origin |
Diseased |
Cell Name 1(En) |
IR-M2 |
Cell Name 1(Ja) |
IR-M2 |
Cell Name 2(En) |
GM10277 |
Cell Name 2(Ja) |
GM10277 |
Disease Name 1(Ja) |
ドナヒュー症候群 |
ICD Code 1 |
E348 |
Disease Name 1(En) |
Donohue Syndrome |
OMIM1 |
246200 |
Disease Name 2(Ja) |
- |
ICD Code 2 |
- |
Disease Name 2(En) |
- |
OMIM 2 |
- |
Disease Name 3(Ja) |
- |
ICD Code 3 |
- |
Disease Name 3(En) |
- |
OMIM 3 |
- |
Age |
15 |
Age Range |
10-19 |
Sex |
Female |
Race(En) |
- |
Race(Ja) |
- |
Genetic Diagnosis |
Yes |
Not Detected |
No |
Description(En) |
Specific disease iPS cell line from patient with Donohue Syndrome |
Description(Ja) |
ドナヒュー症候群患者由来iPS細胞 |
Cell Morphology |
human ES-like |
Grade |
Research Grade |
Vector |
Retrovirus |
Transgene |
KLF4,SOX2,OCT4,C-MYC |
Adhesiveness |
Yes |
Feeder |
No |
Feeder Cell |
- |
Medium |
mTeSR1 |
Genome Editing |
- |
CO2 |
5% |
Mycoplasma |
- |
Detection of Contaminants Mycoplasma |
- |
Pluripotent Markers |
Yes |
Pluripotent Markers Assay |
Immunostaining |
in vitro Differentiation |
- |
in vitro Differentiation Assay |
- |
in vivo Differentiation |
Yes |
in vivo Differentiation Assay |
Teratoma formation |
Other 1 Assay |
- |
Other 1 Assay Method |
- |
Other 2 Assay |
- |
Other 2 Assay Method |
- |
Other 3 Assay |
- |
Other 3 Assay Method |
- |
Karyotype |
- |
Karyotype Assay |
- |
Remaining Vector Detection |
- |
Remaining Vector Detection Assay |
- |
STR |
- |
HLA |
- |
Stem Cell Transcriptome analysis |
- |
Stem Cell Transcriptome analysis Assay |
- |
Author Name(En) |
Salvatore Iovino |
Author Name(Ja) |
Salvatore Iovino |
Author Organization(En) |
Harvard Medical School |
Author Organization(Ja) |
Harvard Medical School |
Author Contact Email |
- |
PI Organization(En) |
Harvard Medical School |
PI Organization(Ja) |
Harvard Medical School |
PI Name(En) |
C. Ronald Kahn |
PI Name(Ja) |
C. Ronald Kahn |
PI Contact Email |
c[dot]ronald[dot]kahn[at]joslin[dot]harvard[dot]edu |
Availability |
Not Available |
Provider Organization(En) |
Harvard Medical School |
Provider Organization(Ja) |
Harvard Medical School |
Provider Email |
c[dot]ronald[dot]kahn[at]joslin[dot]harvard[dot]edu |
Provider URL |
- |
Ethical Statement(En) |
- |
Ethical Statement(Ja) |
- |
Terms of Use(En) |
- |
Terms of Use(Ja) |
- |
PubMed ID |
26831110 |
DOI |
10.1073/pnas.1525665113 |
Title |
Myotubes derived from human-induced pluripotent stem cells mirror in vivo insulin resistance. |
Authors |
Iovino S, Burkart AM, Warren L, Patti ME, Kahn CR |
Journal |
Proc Natl Acad Sci U S A |
Year |
2016 |
Volume |
113 |
Issue |
7 |
Pages |
1889-94 |
URL |
http://www.ncbi.nlm.nih.gov/pubmed/26831110 |
Free input |
- |
Note |
- |