SKIP001068 |
SKIP ID |
SKIP001068 |
Organism(En) |
- |
Organism(Ja) |
- |
Cell Type(En) |
- |
Cell Type(Ja) |
- |
Cell Tissue(En) |
- |
Cell Tissue(Ja) |
- |
Cell Origin |
Diseased |
Cell Name 1(En) |
Trpl17 |
Cell Name 1(Ja) |
Trpl17 |
Cell Name 2(En) |
- |
Cell Name 2(Ja) |
- |
Disease Name 1(Ja) |
家族性パーキンソン病 PARK4 |
ICD Code 1 |
G20 |
Disease Name 1(En) |
Familial PARKINSON DISEASE, PARK4 |
OMIM1 |
605543 |
Disease Name 2(Ja) |
- |
ICD Code 2 |
- |
Disease Name 2(En) |
- |
OMIM 2 |
- |
Disease Name 3(Ja) |
- |
ICD Code 3 |
- |
Disease Name 3(En) |
- |
OMIM 3 |
- |
Age |
42 |
Age Range |
40-49 |
Sex |
Male |
Race(En) |
- |
Race(Ja) |
- |
Genetic Diagnosis |
Yes |
Not Detected |
No |
Description(En) |
Disease specific iPS cell lines derived from patient with Parkinson disease (PARK4) |
Description(Ja) |
パーキンソン病(PARK4)患者由来iPS細胞 |
Cell Morphology |
human ES-like |
Grade |
Research Grade |
Vector |
Retrovirus |
Transgene |
KLF4,SOX2,OCT4,C-MYC |
Adhesiveness |
Yes |
Feeder |
Yes |
Feeder Cell |
MEF |
Medium |
- |
Genome Editing |
- |
CO2 |
5% |
Mycoplasma |
- |
Detection of Contaminants Mycoplasma |
- |
Pluripotent Markers |
Yes |
Pluripotent Markers Assay |
Immunostaining |
in vitro Differentiation |
Yes |
in vitro Differentiation Assay |
EB formation |
in vivo Differentiation |
Yes |
in vivo Differentiation Assay |
Teratoma formation |
Other 1 Assay |
- |
Other 1 Assay Method |
- |
Other 2 Assay |
- |
Other 2 Assay Method |
- |
Other 3 Assay |
- |
Other 3 Assay Method |
- |
Karyotype |
Yes |
Karyotype Assay |
Spectral SKY karyotype analysis |
Remaining Vector Detection |
- |
Remaining Vector Detection Assay |
- |
STR |
- |
HLA |
- |
Stem Cell Transcriptome analysis |
- |
Stem Cell Transcriptome analysis Assay |
- |
Author Name(En) |
Blake Byers |
Author Name(Ja) |
Blake Byers |
Author Organization(En) |
Stanford University |
Author Organization(Ja) |
Stanford University |
Author Contact Email |
- |
PI Organization(En) |
Stanford University |
PI Organization(Ja) |
Stanford University |
PI Name(En) |
Theo D. Palmer |
PI Name(Ja) |
Theo D. Palmer |
PI Contact Email |
tpalmer[at]stanford[dot]edu |
Availability |
Information Only |
Provider Organization(En) |
Stanford University |
Provider Organization(Ja) |
Stanford University |
Provider Email |
tpalmer[at]stanford[dot]edu |
Provider URL |
- |
Ethical Statement(En) |
- |
Ethical Statement(Ja) |
- |
Terms of Use(En) |
- |
Terms of Use(Ja) |
- |
PubMed ID |
22110584 |
DOI |
10.1371/journal.pone.0026159 |
Title |
SNCA triplication Parkinson's patient's iPSC-derived DA neurons accumulate α-synuclein and are susceptible to oxidative stress. |
Authors |
Byers B, Cord B, Nguyen HN, Schule B, Fenno L, Lee PC, Deisseroth K, Langston JW, Pera RR, Palmer TD |
Journal |
PLoS One |
Year |
2011 |
Volume |
6 |
Issue |
11 |
Pages |
e26159 |
URL |
http://www.ncbi.nlm.nih.gov/pubmed/22110584 |
Free input |
- |
Note |
Feeder freeで培養されたiPS細胞も存在 |