SKIP001068
SKIP ID SKIP001068
Organism(En) -
Organism(Ja) -
Cell Type(En) -
Cell Type(Ja) -
Cell Tissue(En) -
Cell Tissue(Ja) -
Cell Origin Diseased
Cell Name 1(En) Trpl17
Cell Name 1(Ja) Trpl17
Cell Name 2(En) -
Cell Name 2(Ja) -
Disease Name 1(Ja) 家族性パーキンソン病 PARK4
ICD Code 1 G20
Disease Name 1(En) Familial PARKINSON DISEASE, PARK4
OMIM1 605543
Disease Name 2(Ja) -
ICD Code 2 -
Disease Name 2(En) -
OMIM 2 -
Disease Name 3(Ja) -
ICD Code 3 -
Disease Name 3(En) -
OMIM 3 -
Age 42
Age Range 40-49
Sex Male
Race(En) -
Race(Ja) -
Genetic Diagnosis Yes
Not Detected No
Description(En) Disease specific iPS cell lines derived from patient with Parkinson disease (PARK4)
Description(Ja) パーキンソン病(PARK4)患者由来iPS細胞
Cell Morphology human ES-like
Grade Research Grade
Vector Retrovirus
Transgene KLF4,SOX2,OCT4,C-MYC
Adhesiveness Yes
Feeder Yes
Feeder Cell MEF
Medium -
Genome Editing -
CO2 5%
Mycoplasma -
Detection of Contaminants Mycoplasma -
Pluripotent Markers Yes
Pluripotent Markers Assay Immunostaining
in vitro Differentiation Yes
in vitro Differentiation Assay EB formation
in vivo Differentiation Yes
in vivo Differentiation Assay Teratoma formation
Other 1 Assay -
Other 1 Assay Method -
Other 2 Assay -
Other 2 Assay Method -
Other 3 Assay -
Other 3 Assay Method -
Karyotype Yes
Karyotype Assay Spectral SKY karyotype analysis
Remaining Vector Detection -
Remaining Vector Detection Assay -
STR -
HLA -
Stem Cell Transcriptome analysis -
Stem Cell Transcriptome analysis Assay -
Author Name(En) Blake Byers
Author Name(Ja) Blake Byers
Author Organization(En) Stanford University
Author Organization(Ja) Stanford University
Author Contact Email -
PI Organization(En) Stanford University
PI Organization(Ja) Stanford University
PI Name(En) Theo D. Palmer
PI Name(Ja) Theo D. Palmer
PI Contact Email tpalmer[at]stanford[dot]edu
Availability Information Only
Provider Organization(En) Stanford University
Provider Organization(Ja) Stanford University
Provider Email tpalmer[at]stanford[dot]edu
Provider URL -
Ethical Statement(En) -
Ethical Statement(Ja) -
Terms of Use(En) -
Terms of Use(Ja) -
PubMed ID 22110584
DOI 10.1371/journal.pone.0026159
Title SNCA triplication Parkinson's patient's iPSC-derived DA neurons accumulate α-synuclein and are susceptible to oxidative stress.
Authors Byers B, Cord B, Nguyen HN, Schule B, Fenno L, Lee PC, Deisseroth K, Langston JW, Pera RR, Palmer TD
Journal PLoS One
Year 2011
Volume 6
Issue 11
Pages e26159
URL http://www.ncbi.nlm.nih.gov/pubmed/22110584
Free input -
Note Feeder freeで培養されたiPS細胞も存在