SKIP000232
SKIP ID SKIP000232
Organism(En) -
Organism(Ja) -
Cell Type(En) -
Cell Type(Ja) -
Cell Tissue(En) -
Cell Tissue(Ja) -
Cell Origin Diseased
Cell Name 1(En) CiRA00026
Cell Name 1(Ja) CiRA00026
Cell Name 2(En) HPS0294
Cell Name 2(Ja) HPS0294
Disease Name 1(Ja) 筋萎縮性側索硬化症
ICD Code 1 G122
Disease Name 1(En) Amyotrophic Lateral Sclerosis
OMIM1 105400
Disease Name 2(Ja) -
ICD Code 2 -
Disease Name 2(En) -
OMIM 2 -
Disease Name 3(Ja) -
ICD Code 3 -
Disease Name 3(En) -
OMIM 3 -
Age -
Age Range 60-69
Sex Female
Race(En) -
Race(Ja) -
Genetic Diagnosis Yes
Not Detected No
Description(En) Amyotrophic lateral scerosis iPS cell line derived from skin fibroblast. TDP-43 mutation Same patient as CiRA00024, CiRA00025.
Description(Ja) 筋萎縮性側索硬化症(TDP-43遺伝子変異) iPS細胞。CiRA00024,25と同一人由来
Cell Morphology human ES-like
Grade --
Vector Plasmid
Transgene Episomal vector, Oct3/4, Sox2, Klf4, L-Myc, Lin28, shp53
Adhesiveness -
Feeder Yes
Feeder Cell SNL 76/7(X-rays:5000R or MMC) 1.5-2.5x10^(6)cells/100mm dish
Medium Primate ES Cell Medium+4ng/mL human basic FGF
Genome Editing -
CO2 -
Mycoplasma -
Detection of Contaminants Mycoplasma -
Pluripotent Markers -
Pluripotent Markers Assay -
in vitro Differentiation -
in vitro Differentiation Assay -
in vivo Differentiation -
in vivo Differentiation Assay -
Other 1 Assay -
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Other 2 Assay -
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Other 3 Assay -
Other 3 Assay Method -
Karyotype -
Karyotype Assay -
Remaining Vector Detection -
Remaining Vector Detection Assay -
STR -
HLA -
Stem Cell Transcriptome analysis -
Stem Cell Transcriptome analysis Assay -
Author Name(En) Haruhisa Inoue
Author Name(Ja) 井上治久
Author Organization(En) Kyoto University, Center for iPS Cell Research and Application
Author Organization(Ja) 京都大学iPS細胞研究所
Author Contact Email -
PI Organization(En) -
PI Organization(Ja) -
PI Name(En) -
PI Name(Ja) -
PI Contact Email -
Availability Available
Provider Organization(En) RIKEN BRC
Provider Organization(Ja) 理研バイオリソースセンター
Provider Email -
Provider URL http://www2.brc.riken.jp/lab/cell/detail.cgi?cell_no=HPS0294&type=1
Ethical Statement(En) -
Ethical Statement(Ja) -
Terms of Use(En) -
Terms of Use(Ja) -
PubMed ID 22855461
DOI 10.1126/scitranslmed.3004052
Title Drug screening for ALS using patient-specific induced pluripotent stem cells.
Authors Egawa N, Kitaoka S, Tsukita K, Naitoh M, Takahashi K, Yamamoto T, Adachi F, Kondo T, Okita K, Asaka I, Aoi T, Watanabe A, Yamada Y, Morizane A, Takahashi J, Ayaki T, Ito H, Yoshikawa K, Yamawaki S, Suzuki S, Watanabe D, Hioki H, Kaneko T, Makioka K, Okamoto K, Takuma H, Tamaoka A, Hasegawa K, Nonaka T, Hasegawa M, Kawata A, Yoshida M, Nakahata T, Takahashi R, Marchetto MC, Gage FH, Yamanaka S, Inoue H
Journal Sci Transl Med
Year 2012
Volume 4
Issue 145
Pages 145ra104
URL http://www.ncbi.nlm.nih.gov/pubmed/22855461
Free input -
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