| SKIP000253 | |
| SKIP ID | SKIP000253 |
| Organism(En) | - |
| Organism(Ja) | - |
| Cell Type(En) | - |
| Cell Type(Ja) | - |
| Cell Tissue(En) | - |
| Cell Tissue(Ja) | - |
| Cell Origin | Diseased |
| Cell Name 1(En) | GM23760 |
| Cell Name 1(Ja) | GM23760 |
| Cell Name 2(En) | - |
| Cell Name 2(Ja) | - |
| Disease Name 1(Ja) | 統合失調症 |
| ICD Code 1 | F20 |
| Disease Name 1(En) | Schizophrenia |
| OMIM1 | 181500 |
| Disease Name 2(Ja) | - |
| ICD Code 2 | - |
| Disease Name 2(En) | - |
| OMIM 2 | - |
| Disease Name 3(Ja) | - |
| ICD Code 3 | - |
| Disease Name 3(En) | - |
| OMIM 3 | - |
| Age | 26 |
| Age Range | 20-29 |
| Sex | Male |
| Race(En) | - |
| Race(Ja) | - |
| Genetic Diagnosis | Yes |
| Not Detected | No |
| Description(En) | iPS cell line derived from GM01792 fibroblast. Clinically affected with Shizophrenia(SCZD) . episodes of agitatation, delusions of persecutation, fear of assassination, father also affected. |
| Description(Ja) | 統合失調症患者線維芽細胞(GM01792)由来iPS細胞株。 |
| Cell Morphology | human ES-like |
| Grade | -- |
| Vector | Retrovirus |
| Transgene | Oct4, Sox2, Klf4, c-Myc, Lin28, retroviral vector |
| Adhesiveness | - |
| Feeder | Yes |
| Feeder Cell | CF1 MEFs on 0.1% Gelatin |
| Medium | KO DMEM+20%KOSR+50ng/mL FGF |
| Genome Editing | - |
| CO2 | - |
| Mycoplasma | - |
| Detection of Contaminants Mycoplasma | - |
| Pluripotent Markers | - |
| Pluripotent Markers Assay | - |
| in vitro Differentiation | - |
| in vitro Differentiation Assay | - |
| in vivo Differentiation | - |
| in vivo Differentiation Assay | - |
| Other 1 Assay | - |
| Other 1 Assay Method | - |
| Other 2 Assay | - |
| Other 2 Assay Method | - |
| Other 3 Assay | - |
| Other 3 Assay Method | - |
| Karyotype | Yes |
| Karyotype Assay | 46,XY |
| Remaining Vector Detection | - |
| Remaining Vector Detection Assay | - |
| STR | - |
| HLA | - |
| Stem Cell Transcriptome analysis | - |
| Stem Cell Transcriptome analysis Assay | - |
| Author Name(En) | Fred H. Gage |
| Author Name(Ja) | Fred H. Gage |
| Author Organization(En) | Salk Institute for Biological Studies UCSD |
| Author Organization(Ja) | Salk Institute for Biological Studies UCSD |
| Author Contact Email | - |
| PI Organization(En) | NIGMS Coriell Cell Repository |
| PI Organization(Ja) | NIGMS Coriell Cell Repository |
| PI Name(En) | NIGMS Human Genetic Cell Repository |
| PI Name(Ja) | NIGMS Human Genetic Cell Repository |
| PI Contact Email | - |
| Availability | Available |
| Provider Organization(En) | NIGMS Coriell Cell Repository |
| Provider Organization(Ja) | NIGMS Coriell Cell Repository |
| Provider Email | - |
| Provider URL | http://ccr.coriell.org/Sections/Search/Sample_Detail.aspx?Ref=GM23760&PgId=166 |
| Ethical Statement(En) | - |
| Ethical Statement(Ja) | - |
| Terms of Use(En) | - |
| Terms of Use(Ja) | - |
| PubMed ID | 21490598 |
| DOI | 10.1038/nature09915 |
| Title | Modelling schizophrenia using human induced pluripotent stem cells. |
| Authors | Brennand KJ, Simone A, Jou J, Gelboin-Burkhart C, Tran N, Sangar S, Li Y, Mu Y, Chen G, Yu D, McCarthy S, Sebat J, Gage FH |
| Journal | Nature |
| Year | 2011 |
| Volume | 473 |
| Issue | 7346 |
| Pages | 221-5 |
| URL | http://www.ncbi.nlm.nih.gov/pubmed/21490598 |
| Free input | - |
| Note | 保存：Tryple |