SKIP000260 |
SKIP ID |
SKIP000260 |
Organism(En) |
- |
Organism(Ja) |
- |
Cell Type(En) |
- |
Cell Type(Ja) |
- |
Cell Tissue(En) |
- |
Cell Tissue(Ja) |
- |
Cell Origin |
Diseased |
Cell Name 1(En) |
GM23761 |
Cell Name 1(Ja) |
GM23761 |
Cell Name 2(En) |
- |
Cell Name 2(Ja) |
- |
Disease Name 1(Ja) |
統合失調症 |
ICD Code 1 |
F20 |
Disease Name 1(En) |
Schizophrenia |
OMIM1 |
181500 |
Disease Name 2(Ja) |
- |
ICD Code 2 |
- |
Disease Name 2(En) |
- |
OMIM 2 |
- |
Disease Name 3(Ja) |
- |
ICD Code 3 |
- |
Disease Name 3(En) |
- |
OMIM 3 |
- |
Age |
27 |
Age Range |
20-29 |
Sex |
Female |
Race(En) |
Jewish |
Race(Ja) |
Jewish |
Genetic Diagnosis |
Yes |
Not Detected |
No |
Description(En) |
iPS cell line derived from GM01835 fibroblast. Clinically affected with Shizophrenia(SCZD) .
|
Description(Ja) |
統合失調症患者線維芽細胞(GM01835)由来iPS細胞株
|
Cell Morphology |
human ES-like |
Grade |
-- |
Vector |
Lentivirus |
Transgene |
Oct4, Sox2, Klf4, c-Myc, Lin28,lentivirous vector |
Adhesiveness |
- |
Feeder |
Yes |
Feeder Cell |
CF1 MEFs on 0.1% Gelatin |
Medium |
KO DMEM+20%KOSR+50ng/mL FGF |
Genome Editing |
- |
CO2 |
- |
Mycoplasma |
- |
Detection of Contaminants Mycoplasma |
- |
Pluripotent Markers |
- |
Pluripotent Markers Assay |
- |
in vitro Differentiation |
- |
in vitro Differentiation Assay |
- |
in vivo Differentiation |
- |
in vivo Differentiation Assay |
- |
Other 1 Assay |
- |
Other 1 Assay Method |
- |
Other 2 Assay |
- |
Other 2 Assay Method |
- |
Other 3 Assay |
- |
Other 3 Assay Method |
- |
Karyotype |
Yes |
Karyotype Assay |
46,XX |
Remaining Vector Detection |
- |
Remaining Vector Detection Assay |
- |
STR |
- |
HLA |
- |
Stem Cell Transcriptome analysis |
- |
Stem Cell Transcriptome analysis Assay |
- |
Author Name(En) |
Fred H. Gage |
Author Name(Ja) |
Fred H. Gage |
Author Organization(En) |
Salk Institute for Biological Studies UCSD |
Author Organization(Ja) |
Salk Institute for Biological Studies UCSD |
Author Contact Email |
- |
PI Organization(En) |
NIGMS Coriell Cell Repository |
PI Organization(Ja) |
NIGMS Coriell Cell Repository |
PI Name(En) |
NIGMS Human Genetic Cell Repository |
PI Name(Ja) |
NIGMS Human Genetic Cell Repository |
PI Contact Email |
- |
Availability |
Available |
Provider Organization(En) |
NIGMS Coriell Cell Repository |
Provider Organization(Ja) |
NIGMS Coriell Cell Repository |
Provider Email |
- |
Provider URL |
http://ccr.coriell.org/Sections/Search/Sample_Detail.aspx?Ref=GM23761&PgId=166 |
Ethical Statement(En) |
- |
Ethical Statement(Ja) |
- |
Terms of Use(En) |
- |
Terms of Use(Ja) |
- |
PubMed ID |
21490598 |
DOI |
10.1038/nature09915 |
Title |
Modelling schizophrenia using human induced pluripotent stem cells. |
Authors |
Brennand KJ, Simone A, Jou J, Gelboin-Burkhart C, Tran N, Sangar S, Li Y, Mu Y, Chen G, Yu D, McCarthy S, Sebat J, Gage FH |
Journal |
Nature |
Year |
2011 |
Volume |
473 |
Issue |
7346 |
Pages |
221-5 |
URL |
http://www.ncbi.nlm.nih.gov/pubmed/21490598 |
Free input |
- |
Note |
保存:Tryple
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