SKIP000327
SKIP ID SKIP000327
Organism(En) -
Organism(Ja) -
Cell Type(En) -
Cell Type(Ja) -
Cell Tissue(En) -
Cell Tissue(Ja) -
Cell Origin Diseased
Cell Name 1(En) Carrier2 #11
Cell Name 1(Ja) Carrier2 #11
Cell Name 2(En) -
Cell Name 2(Ja) -
Disease Name 1(Ja) 前頭側頭型認知症
ICD Code 1 G310
Disease Name 1(En) FrontoTemporal Dementia
OMIM1 10550
Disease Name 2(Ja) 筋萎縮性側索硬化症
ICD Code 2 G122
Disease Name 2(En) Amytrophic Lateral Sclerosis
OMIM 2 10550
Disease Name 3(Ja) -
ICD Code 3 -
Disease Name 3(En) -
OMIM 3 -
Age -
Age Range --
Sex --
Race(En) -
Race(Ja) -
Genetic Diagnosis Yes
Not Detected No
Description(En) >1000 GGGGCC repeats in C9ORF72
Description(Ja) >1000 GGGGCC repeats in C9ORF72
Cell Morphology --
Grade Research Grade
Vector Retrovirus
Transgene OCT3/4, SOX2, KLF4, c-MYC
Adhesiveness -
Feeder No
Feeder Cell -
Medium mTeSR1 medium
Genome Editing -
CO2 -
Mycoplasma -
Detection of Contaminants Mycoplasma -
Pluripotent Markers Yes
Pluripotent Markers Assay Immunocytochemistry
in vitro Differentiation Yes
in vitro Differentiation Assay Immunocytochemistry
in vivo Differentiation No
in vivo Differentiation Assay -
Other 1 Assay Yes
Other 1 Assay Method Southern blot
Other 2 Assay Yes
Other 2 Assay Method Immunocytochemistr
Other 3 Assay Yes
Other 3 Assay Method Electrophysiology
Karyotype Yes
Karyotype Assay G-banding
Remaining Vector Detection Yes
Remaining Vector Detection Assay quantitative RT-PCR
STR No
HLA No
Stem Cell Transcriptome analysis No
Stem Cell Transcriptome analysis Assay -
Author Name(En) Fen-Biao Gao
Author Name(Ja) Fen-Biao Gao
Author Organization(En) Department of Neurology, University of Massachusetts Medical School
Author Organization(Ja) Department of Neurology, University of Massachusetts Medical School
Author Contact Email -
PI Organization(En) -
PI Organization(Ja) -
PI Name(En) -
PI Name(Ja) -
PI Contact Email -
Availability Information Only
Provider Organization(En) Department of Neurology, University of Massachusetts Medical School
Provider Organization(Ja) Department of Neurology, University of Massachusetts Medical School
Provider Email -
Provider URL -
Ethical Statement(En) -
Ethical Statement(Ja) -
Terms of Use(En) -
Terms of Use(Ja) -
PubMed ID 23836290
DOI 10.1007/s00401-013-1149-y
Title Modeling key pathological features of frontotemporal dementia with C9ORF72 repeat expansion in iPSC-derived human neurons.
Authors Almeida S, Gascon E, Tran H, Chou HJ, Gendron TF, Degroot S, Tapper AR, Sellier C, Charlet-Berguerand N, Karydas A, Seeley WW, Boxer AL, Petrucelli L, Miller BL, Gao FB
Journal Acta Neuropathol
Year 2013
Volume 126
Issue 3
Pages 385-99
URL http://www.ncbi.nlm.nih.gov/pubmed/23836290
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