| SKIP000303 | |
| SKIP ID | SKIP000303 |
| Organism(En) | - |
| Organism(Ja) | - |
| Cell Type(En) | - |
| Cell Type(Ja) | - |
| Cell Tissue(En) | keratinocytes |
| Cell Tissue(Ja) | keratinocytes |
| Cell Origin | Diseased |
| Cell Name 1(En) | USH2A-associated iPSC (tentative) |
| Cell Name 1(Ja) | USH2A-associated iPSC (tentative) |
| Cell Name 2(En) | - |
| Cell Name 2(Ja) | - |
| Disease Name 1(Ja) | 網膜色素変性 |
| ICD Code 1 | H355 |
| Disease Name 1(En) | Retinitis pigmentosa |
| OMIM1 | 268000 |
| Disease Name 2(Ja) | - |
| ICD Code 2 | - |
| Disease Name 2(En) | - |
| OMIM 2 | - |
| Disease Name 3(Ja) | - |
| ICD Code 3 | - |
| Disease Name 3(En) | - |
| OMIM 3 | - |
| Age | - |
| Age Range | 60-69 |
| Sex | Unknown |
| Race(En) | - |
| Race(Ja) | - |
| Genetic Diagnosis | Yes |
| Not Detected | No |
| Description(En) | iPSCs from RP patient with resessive mutation in USH2A, which endodes a protein called usherin. Mutation of USH2A cause Usher syndrome. |
| Description(Ja) | iPSCs from RP patient with resessive mutation in USH2A, which endodes a protein called usherin. Mutation of USH2A cause Usher syndrome. |
| Cell Morphology | human ES-like |
| Grade | Research Grade |
| Vector | Sendai virus |
| Transgene | OCT4, SOX2, KLF4, c-MYC |
| Adhesiveness | - |
| Feeder | No |
| Feeder Cell | - |
| Medium | (DMEM F-12 media [Gibco], 20% knockout serum replacement [Gibco], 0.0008% beta-mercaptoethanol |
| Genome Editing | - |
| CO2 | - |
| Mycoplasma | - |
| Detection of Contaminants Mycoplasma | - |
| Pluripotent Markers | Yes |
| Pluripotent Markers Assay | RT-PCR |
| in vitro Differentiation | No |
| in vitro Differentiation Assay | - |
| in vivo Differentiation | Yes |
| in vivo Differentiation Assay | teratoma formation |
| Other 1 Assay | - |
| Other 1 Assay Method | - |
| Other 2 Assay | - |
| Other 2 Assay Method | - |
| Other 3 Assay | - |
| Other 3 Assay Method | - |
| Karyotype | No |
| Karyotype Assay | - |
| Remaining Vector Detection | No |
| Remaining Vector Detection Assay | - |
| STR | No |
| HLA | No |
| Stem Cell Transcriptome analysis | No |
| Stem Cell Transcriptome analysis Assay | - |
| Author Name(En) | Edwin M Stone |
| Author Name(Ja) | Edwin M Stone |
| Author Organization(En) | University of Iowa Carver College of Medicine |
| Author Organization(Ja) | University of Iowa Carver College of Medicine |
| Author Contact Email | - |
| PI Organization(En) | - |
| PI Organization(Ja) | - |
| PI Name(En) | - |
| PI Name(Ja) | - |
| PI Contact Email | - |
| Availability | Information Only |
| Provider Organization(En) | University of Iowa Carver College of Medicine |
| Provider Organization(Ja) | University of Iowa Carver College of Medicine |
| Provider Email | - |
| Provider URL | - |
| Ethical Statement(En) | - |
| Ethical Statement(Ja) | - |
| Terms of Use(En) | - |
| Terms of Use(Ja) | - |
| PubMed ID | 23991284 |
| DOI | 10.7554/eLife.00824 |
| Title | Patient-specific iPSC-derived photoreceptor precursor cells as a means to investigate retinitis pigmentosa. |
| Authors | Tucker BA, Mullins RF, Streb LM, Anfinson K, Eyestone ME, Kaalberg E, Riker MJ, Drack AV, Braun TA, Stone EM |
| Journal | Elife |
| Year | 2013 |
| Volume | 2 |
| Issue | - |
| Pages | e00824 |
| URL | http://www.ncbi.nlm.nih.gov/pubmed/23991284 |
| Free input | - |
| Note | - |