SKIP000338
SKIP ID SKIP000338
Organism(En) -
Organism(Ja) -
Cell Type(En) -
Cell Type(Ja) -
Cell Tissue(En) -
Cell Tissue(Ja) -
Cell Origin Diseased
Cell Name 1(En) vFOP4-3
Cell Name 1(Ja) vFOP4-3
Cell Name 2(En) -
Cell Name 2(Ja) -
Disease Name 1(Ja) 進行性骨化性線維異形成症
ICD Code 1 M6119
Disease Name 1(En) Fibrodysplasia ossificans progressiva (FOP)
OMIM1 135100
Disease Name 2(Ja) -
ICD Code 2 -
Disease Name 2(En) -
OMIM 2 -
Disease Name 3(Ja) -
ICD Code 3 -
Disease Name 3(En) -
OMIM 3 -
Age 12
Age Range 10-19
Sex Male
Race(En) Japanese
Race(Ja) Japanese
Genetic Diagnosis Yes
Not Detected No
Description(En) hiPSC derived from primary human dermal fibroblasts (HDFs)
Description(Ja) FOP疾患者由来iSP細胞。
レトロウイルスを用いて作製。
Cell Morphology --
Grade Research Grade
Vector Retrovirus
Transgene OCT4, SOX2, KLF4, c-MYC
Adhesiveness -
Feeder Yes
Feeder Cell SNL feeder cells
Medium primate ES cell medium(ReproCELL)
Genome Editing -
CO2 -
Mycoplasma -
Detection of Contaminants Mycoplasma -
Pluripotent Markers Yes
Pluripotent Markers Assay RT-PCR
in vitro Differentiation -
in vitro Differentiation Assay -
in vivo Differentiation Yes
in vivo Differentiation Assay teratoma formation assay
Other 1 Assay Yes
Other 1 Assay Method in vitro chondrogenesis assay
Other 2 Assay -
Other 2 Assay Method -
Other 3 Assay -
Other 3 Assay Method -
Karyotype Yes
Karyotype Assay G-band
Remaining Vector Detection Yes
Remaining Vector Detection Assay -
STR -
HLA -
Stem Cell Transcriptome analysis -
Stem Cell Transcriptome analysis Assay -
Author Name(En) Yoshihisa Matsumoto
Author Name(Ja) 松本 佳久
Author Organization(En) Kyoto University
Author Organization(Ja) 京都大学 再生医科学研究所
Author Contact Email -
PI Organization(En) -
PI Organization(Ja) -
PI Name(En) -
PI Name(Ja) -
PI Contact Email -
Availability Information Only
Provider Organization(En) -
Provider Organization(Ja) -
Provider Email -
Provider URL -
Ethical Statement(En) -
Ethical Statement(Ja) -
Terms of Use(En) -
Terms of Use(Ja) -
PubMed ID 24321451
DOI 10.1186/1750-1172-8-190
Title Induced pluripotent stem cells from patients with human fibrodysplasia ossificans progressiva show increased mineralization and cartilage formation.
Authors Matsumoto Y, Hayashi Y, Schlieve CR, Ikeya M, Kim H, Nguyen TD, Sami S, Baba S, Barruet E, Nasu A, Asaka I, Otsuka T, Yamanaka S, Conklin BR, Toguchida J, Hsiao EC
Journal Orphanet J Rare Dis
Year 2013
Volume 8
Issue -
Pages 190
URL http://www.ncbi.nlm.nih.gov/pubmed/?term=24321451
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