SKIP000338 | |
SKIP ID | SKIP000338 |
Organism(En) | - |
Organism(Ja) | - |
Cell Type(En) | - |
Cell Type(Ja) | - |
Cell Tissue(En) | - |
Cell Tissue(Ja) | - |
Cell Origin | Diseased |
Cell Name 1(En) | vFOP4-3 |
Cell Name 1(Ja) | vFOP4-3 |
Cell Name 2(En) | - |
Cell Name 2(Ja) | - |
Disease Name 1(Ja) | 進行性骨化性線維異形成症 |
ICD Code 1 | M6119 |
Disease Name 1(En) | Fibrodysplasia ossificans progressiva (FOP) |
OMIM1 | 135100 |
Disease Name 2(Ja) | - |
ICD Code 2 | - |
Disease Name 2(En) | - |
OMIM 2 | - |
Disease Name 3(Ja) | - |
ICD Code 3 | - |
Disease Name 3(En) | - |
OMIM 3 | - |
Age | 12 |
Age Range | 10-19 |
Sex | Male |
Race(En) | Japanese |
Race(Ja) | Japanese |
Genetic Diagnosis | Yes |
Not Detected | No |
Description(En) | hiPSC derived from primary human dermal fibroblasts (HDFs) |
Description(Ja) | FOP疾患者由来iSP細胞。 レトロウイルスを用いて作製。 |
Cell Morphology | -- |
Grade | Research Grade |
Vector | Retrovirus |
Transgene | OCT4, SOX2, KLF4, c-MYC |
Adhesiveness | - |
Feeder | Yes |
Feeder Cell | SNL feeder cells |
Medium | primate ES cell medium(ReproCELL) |
Genome Editing | - |
CO2 | - |
Mycoplasma | - |
Detection of Contaminants Mycoplasma | - |
Pluripotent Markers | Yes |
Pluripotent Markers Assay | RT-PCR |
in vitro Differentiation | - |
in vitro Differentiation Assay | - |
in vivo Differentiation | Yes |
in vivo Differentiation Assay | teratoma formation assay |
Other 1 Assay | Yes |
Other 1 Assay Method | in vitro chondrogenesis assay |
Other 2 Assay | - |
Other 2 Assay Method | - |
Other 3 Assay | - |
Other 3 Assay Method | - |
Karyotype | Yes |
Karyotype Assay | G-band |
Remaining Vector Detection | Yes |
Remaining Vector Detection Assay | - |
STR | - |
HLA | - |
Stem Cell Transcriptome analysis | - |
Stem Cell Transcriptome analysis Assay | - |
Author Name(En) | Yoshihisa Matsumoto |
Author Name(Ja) | 松本 佳久 |
Author Organization(En) | Kyoto University |
Author Organization(Ja) | 京都大学 再生医科学研究所 |
Author Contact Email | - |
PI Organization(En) | - |
PI Organization(Ja) | - |
PI Name(En) | - |
PI Name(Ja) | - |
PI Contact Email | - |
Availability | Information Only |
Provider Organization(En) | - |
Provider Organization(Ja) | - |
Provider Email | - |
Provider URL | - |
Ethical Statement(En) | - |
Ethical Statement(Ja) | - |
Terms of Use(En) | - |
Terms of Use(Ja) | - |
PubMed ID | 24321451 |
DOI | 10.1186/1750-1172-8-190 |
Title | Induced pluripotent stem cells from patients with human fibrodysplasia ossificans progressiva show increased mineralization and cartilage formation. |
Authors | Matsumoto Y, Hayashi Y, Schlieve CR, Ikeya M, Kim H, Nguyen TD, Sami S, Baba S, Barruet E, Nasu A, Asaka I, Otsuka T, Yamanaka S, Conklin BR, Toguchida J, Hsiao EC |
Journal | Orphanet J Rare Dis |
Year | 2013 |
Volume | 8 |
Issue | - |
Pages | 190 |
URL | http://www.ncbi.nlm.nih.gov/pubmed/?term=24321451 |
Free input | - |
Note | - |