SKIP000194 |
SKIP ID |
SKIP000194 |
Organism(En) |
- |
Organism(Ja) |
- |
Cell Type(En) |
Fibroblast |
Cell Type(Ja) |
線維芽細胞 |
Cell Tissue(En) |
- |
Cell Tissue(Ja) |
- |
Cell Origin |
Diseased |
Cell Name 1(En) |
PARK4-4 |
Cell Name 1(Ja) |
PARK4-4 |
Cell Name 2(En) |
- |
Cell Name 2(Ja) |
- |
Disease Name 1(Ja) |
家族性パーキンソン病 |
ICD Code 1 |
G20 |
Disease Name 1(En) |
familial parkinson's disease PARK2 |
OMIM1 |
600116 |
Disease Name 2(Ja) |
- |
ICD Code 2 |
- |
Disease Name 2(En) |
- |
OMIM 2 |
- |
Disease Name 3(Ja) |
- |
ICD Code 3 |
- |
Disease Name 3(En) |
- |
OMIM 3 |
- |
Age |
- |
Age Range |
-- |
Sex |
-- |
Race(En) |
- |
Race(Ja) |
- |
Genetic Diagnosis |
Yes |
Not Detected |
No |
Description(En) |
PARK4 iPSC derived from Coriell ID:ND27760 triplication of alpha synuclein gene |
Description(Ja) |
PARK4 iPSC derived from Coriell ID:ND27760 triplication of alpha synuclein gene |
Cell Morphology |
-- |
Grade |
-- |
Vector |
Retrovirus |
Transgene |
Retroviral Vector pDON-5, OCT3/4-SOX2, pDON-5, KLF4, pDON-5, LIN28-NANG |
Adhesiveness |
- |
Feeder |
-- |
Feeder Cell |
- |
Medium |
Dulbecco's Modified Eagle's Medium (Gibco) containing 10% fetal bovine serum, 50 U/mL penicillin, 50 mg/mL streptomycin, and 1 mM L-glutamine |
Genome Editing |
- |
CO2 |
- |
Mycoplasma |
- |
Detection of Contaminants Mycoplasma |
- |
Pluripotent Markers |
- |
Pluripotent Markers Assay |
- |
in vitro Differentiation |
- |
in vitro Differentiation Assay |
- |
in vivo Differentiation |
- |
in vivo Differentiation Assay |
- |
Other 1 Assay |
- |
Other 1 Assay Method |
- |
Other 2 Assay |
- |
Other 2 Assay Method |
- |
Other 3 Assay |
- |
Other 3 Assay Method |
- |
Karyotype |
- |
Karyotype Assay |
- |
Remaining Vector Detection |
- |
Remaining Vector Detection Assay |
- |
STR |
- |
HLA |
- |
Stem Cell Transcriptome analysis |
- |
Stem Cell Transcriptome analysis Assay |
- |
Author Name(En) |
Daisuke Ito |
Author Name(Ja) |
伊東 大介 |
Author Organization(En) |
Keio University |
Author Organization(Ja) |
慶應義塾大学医学部神経内科 |
Author Contact Email |
- |
PI Organization(En) |
Keio University |
PI Organization(Ja) |
慶應義塾大学医学部神経内科 |
PI Name(En) |
Norihiro Suzuki |
PI Name(Ja) |
鈴木 則宏 |
PI Contact Email |
- |
Availability |
Not Available |
Provider Organization(En) |
Keio University |
Provider Organization(Ja) |
慶應義塾大学医学部神経内科 |
Provider Email |
d-ito[at]jk9[dot]so-net[dot]ne[dot]jp |
Provider URL |
- |
Ethical Statement(En) |
- |
Ethical Statement(Ja) |
- |
Terms of Use(En) |
- |
Terms of Use(Ja) |
- |
PubMed ID |
22848530 |
DOI |
10.1371/journal.pone.0041572 |
Title |
Establishment of induced pluripotent stem cells from centenarians for neurodegenerative disease research. |
Authors |
Yagi T, Kosakai A, Ito D, Okada Y, Akamatsu W, Nihei Y, Nabetani A, Ishikawa F, Arai Y, Hirose N, Okano H, Suzuki N |
Journal |
PLoS One |
Year |
2012 |
Volume |
7 |
Issue |
7 |
Pages |
e41572 |
URL |
http://www.ncbi.nlm.nih.gov/pubmed/?term=22848530 |
Free input |
- |
Note |
- |