SKIP000195
SKIP ID SKIP000195
Organism(En) -
Organism(Ja) -
Cell Type(En) Fibroblast
Cell Type(Ja) 線維芽細胞
Cell Tissue(En) -
Cell Tissue(Ja) -
Cell Origin Diseased
Cell Name 1(En) PARK4-14
Cell Name 1(Ja) PARK4-14
Cell Name 2(En) -
Cell Name 2(Ja) -
Disease Name 1(Ja) 家族性パーキンソン病
ICD Code 1 G20
Disease Name 1(En) familial parkinson's disease PARK2
OMIM1 600116
Disease Name 2(Ja) -
ICD Code 2 -
Disease Name 2(En) -
OMIM 2 -
Disease Name 3(Ja) -
ICD Code 3 -
Disease Name 3(En) -
OMIM 3 -
Age -
Age Range --
Sex --
Race(En) -
Race(Ja) -
Genetic Diagnosis Yes
Not Detected No
Description(En) PARK4 iPSC derived from Coriell ID:ND27760 triplication of alpha synuclein gene
Description(Ja) PARK4 iPSC derived from Coriell ID:ND27760 triplication of alpha synuclein gene
Cell Morphology --
Grade --
Vector Retrovirus
Transgene Retroviral Vector pDON-5, OCT3/4-SOX2, pDON-5, KLF4, pDON-5, LIN28-NANG
Adhesiveness -
Feeder --
Feeder Cell -
Medium Dulbecco's Modified Eagle's Medium (Gibco) containing 10% fetal bovine serum, 50 U/mL penicillin, 50 mg/mL streptomycin, and 1 mM L-glutamine
Genome Editing -
CO2 -
Mycoplasma -
Detection of Contaminants Mycoplasma -
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Pluripotent Markers Assay -
in vitro Differentiation -
in vitro Differentiation Assay -
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in vivo Differentiation Assay -
Other 1 Assay -
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Karyotype -
Karyotype Assay -
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Remaining Vector Detection Assay -
STR -
HLA -
Stem Cell Transcriptome analysis -
Stem Cell Transcriptome analysis Assay -
Author Name(En) Daisuke Ito
Author Name(Ja) 伊東 大介
Author Organization(En) Keio University
Author Organization(Ja) 慶應義塾大学医学部神経内科
Author Contact Email -
PI Organization(En) Keio University
PI Organization(Ja) 慶應義塾大学医学部神経内科
PI Name(En) Norihiro Suzuki
PI Name(Ja) 鈴木 則宏
PI Contact Email -
Availability Not Available
Provider Organization(En) Keio University
Provider Organization(Ja) 慶應義塾大学医学部神経内科
Provider Email d-ito[at]jk9[dot]so-net[dot]ne[dot]jp
Provider URL -
Ethical Statement(En) -
Ethical Statement(Ja) -
Terms of Use(En) -
Terms of Use(Ja) -
PubMed ID 22848530
DOI 10.1371/journal.pone.0041572
Title Establishment of induced pluripotent stem cells from centenarians for neurodegenerative disease research.
Authors Yagi T, Kosakai A, Ito D, Okada Y, Akamatsu W, Nihei Y, Nabetani A, Ishikawa F, Arai Y, Hirose N, Okano H, Suzuki N
Journal PLoS One
Year 2012
Volume 7
Issue 7
Pages e41572
URL http://www.ncbi.nlm.nih.gov/pubmed/?term=22848530
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