SKIP000939 |
SKIP ID |
SKIP000939 |
Organism(En) |
- |
Organism(Ja) |
- |
Cell Type(En) |
- |
Cell Type(Ja) |
- |
Cell Tissue(En) |
dermal fibroblast |
Cell Tissue(Ja) |
表皮繊維芽細胞 |
Cell Origin |
Diseased |
Cell Name 1(En) |
SP02.2 |
Cell Name 1(Ja) |
SP02.2 |
Cell Name 2(En) |
- |
Cell Name 2(Ja) |
- |
Disease Name 1(Ja) |
パーキンソン病 |
ICD Code 1 |
G20 |
Disease Name 1(En) |
Parkinson disease |
OMIM1 |
168006 |
Disease Name 2(Ja) |
- |
ICD Code 2 |
- |
Disease Name 2(En) |
- |
OMIM 2 |
- |
Disease Name 3(Ja) |
- |
ICD Code 3 |
- |
Disease Name 3(En) |
- |
OMIM 3 |
- |
Age |
55 |
Age Range |
50-59 |
Sex |
Male |
Race(En) |
- |
Race(Ja) |
- |
Genetic Diagnosis |
No |
Not Detected |
No |
Description(En) |
iPS cell line |
Description(Ja) |
iPS細胞 |
Cell Morphology |
human ES-like |
Grade |
Research Grade |
Vector |
Retrovirus |
Transgene |
SOX2, KLF4 and OCT3/4 |
Adhesiveness |
Yes |
Feeder |
Yes |
Feeder Cell |
MEFs |
Medium |
Lines of patient-specific iPS cells were maintained by mechanical dissociation of colonies and splitting 1:3 onto feeder cells in hESC medium or by limited trypsin digestion and passaging onto Matrigel-coated plates with hESC medium pre-conditioned by mouse embryonic fibroblasts. |
Genome Editing |
- |
CO2 |
- |
Mycoplasma |
- |
Detection of Contaminants Mycoplasma |
- |
Pluripotent Markers |
Yes |
Pluripotent Markers Assay |
immunocytochemistry |
in vitro Differentiation |
Yes |
in vitro Differentiation Assay |
differentiation to three germ layers |
in vivo Differentiation |
No |
in vivo Differentiation Assay |
- |
Other 1 Assay |
- |
Other 1 Assay Method |
- |
Other 2 Assay |
- |
Other 2 Assay Method |
- |
Other 3 Assay |
- |
Other 3 Assay Method |
- |
Karyotype |
Yes |
Karyotype Assay |
- |
Remaining Vector Detection |
Yes |
Remaining Vector Detection Assay |
qRT-PCR |
STR |
- |
HLA |
- |
Stem Cell Transcriptome analysis |
Yes |
Stem Cell Transcriptome analysis Assay |
qRT-PCR |
Author Name(En) |
Adriana Sanchez-Danes |
Author Name(Ja) |
Adriana Sanchez-Danes |
Author Organization(En) |
Institute for Biomedicine (IBUB), University of Barcelona, |
Author Organization(Ja) |
Institute for Biomedicine (IBUB), University of Barcelona, |
Author Contact Email |
aconsiglio[at]pcb[dot]ub[dot]es |
PI Organization(En) |
- |
PI Organization(Ja) |
- |
PI Name(En) |
- |
PI Name(Ja) |
- |
PI Contact Email |
- |
Availability |
Available |
Provider Organization(En) |
Spanish Stem Cell Bank |
Provider Organization(Ja) |
Spanish Stem Cell Bank |
Provider Email |
aconsiglio[at]pcb[dot]ub[dot]es |
Provider URL |
- |
Ethical Statement(En) |
- |
Ethical Statement(Ja) |
- |
Terms of Use(En) |
- |
Terms of Use(Ja) |
- |
PubMed ID |
22407749 |
DOI |
10.1002/emmm.201200215 |
Title |
Disease-specific phenotypes in dopamine neurons from human iPS-based models of genetic and sporadic Parkinson's disease. |
Authors |
Sanchez-Danes A, Richaud-Patin Y, Carballo-Carbajal I, Jimenez-Delgado S, Caig C, Mora S, Di Guglielmo C, Ezquerra M, Patel B, Giralt A, Canals JM, Memo M, Alberch J, Lopez-Barneo J, Vila M, Cuervo AM, Tolosa E, Consiglio A, Raya A |
Journal |
EMBO Mol Med |
Year |
2012 |
Volume |
4 |
Issue |
5 |
Pages |
380-95 |
URL |
http://www.ncbi.nlm.nih.gov/pubmed/22407749 |
Free input |
- |
Note |
- |