| SKIP000635 | |
| SKIP ID | SKIP000635 |
| Organism(En) | - |
| Organism(Ja) | - |
| Cell Type(En) | - |
| Cell Type(Ja) | - |
| Cell Tissue(En) | - |
| Cell Tissue(Ja) | - |
| Cell Origin | Diseased |
| Cell Name 1(En) | CiRA00041 |
| Cell Name 1(Ja) | CiRA00041 |
| Cell Name 2(En) | HPS0376 |
| Cell Name 2(Ja) | HPS0376 |
| Disease Name 1(Ja) | 進行性骨化性線維異形成症 |
| ICD Code 1 | M6119 |
| Disease Name 1(En) | Fibrodysplasia ossificans progressiva (FOP) |
| OMIM1 | 135100 |
| Disease Name 2(Ja) | - |
| ICD Code 2 | - |
| Disease Name 2(En) | - |
| OMIM 2 | - |
| Disease Name 3(Ja) | - |
| ICD Code 3 | - |
| Disease Name 3(En) | - |
| OMIM 3 | - |
| Age | - |
| Age Range | -- |
| Sex | -- |
| Race(En) | Japanese |
| Race(Ja) | Japanese |
| Genetic Diagnosis | Yes |
| Not Detected | No |
| Description(En) | Disease specific iPS cell line derived from a patient : Fibrodysplasia ossificans progressiva (FOP) |
| Description(Ja) | 進行性骨化性線維異形成症患者由来iPS細胞。 |
| Cell Morphology | human ES-like |
| Grade | Research Grade |
| Vector | Retrovirus |
| Transgene | mouse Slc7a, pMXs-Oct3/4, -Sox2, -Klf4, c-Myc |
| Adhesiveness | - |
| Feeder | Yes |
| Feeder Cell | SNL 76/7 (X-rays:5000R or MMC) 1.5-2.5x10^(6) cells/100mm dish |
| Medium | Primate ES Cell Medium+4ng/ml human basic FGF |
| Genome Editing | - |
| CO2 | 5% |
| Mycoplasma | Negative |
| Detection of Contaminants Mycoplasma | - |
| Pluripotent Markers | - |
| Pluripotent Markers Assay | - |
| in vitro Differentiation | - |
| in vitro Differentiation Assay | - |
| in vivo Differentiation | - |
| in vivo Differentiation Assay | - |
| Other 1 Assay | - |
| Other 1 Assay Method | - |
| Other 2 Assay | - |
| Other 2 Assay Method | - |
| Other 3 Assay | - |
| Other 3 Assay Method | - |
| Karyotype | - |
| Karyotype Assay | - |
| Remaining Vector Detection | - |
| Remaining Vector Detection Assay | - |
| STR | Yes |
| HLA | - |
| Stem Cell Transcriptome analysis | - |
| Stem Cell Transcriptome analysis Assay | - |
| Author Name(En) | Yoshihira Matsumoto |
| Author Name(Ja) | 松本 佳久 |
| Author Organization(En) | Kyoto University |
| Author Organization(Ja) | 京都大学 再生医科学研究所 |
| Author Contact Email | cellips[at]brc[dot]riken[dot]jp |
| PI Organization(En) | RIKEN BioResource Center |
| PI Organization(Ja) | 理化学研究所バイオリソースセンター |
| PI Name(En) | RIKEN BioResource Center |
| PI Name(Ja) | 理化学研究所バイオリソースセンター |
| PI Contact Email | cellips[at]brc[dot]riken[dot]jp |
| Availability | Available |
| Provider Organization(En) | RIKEN BioResource Center |
| Provider Organization(Ja) | 理化学研究所バイオリソースセンター |
| Provider Email | cellips[at]brc[dot]riken[dot]jp |
| Provider URL | http://www2.brc.riken.jp/lab/cell/detail.cgi?cell_no=HPS0376&type=1 |
| Ethical Statement(En) | - |
| Ethical Statement(Ja) | - |
| Terms of Use(En) | - |
| Terms of Use(Ja) | - |
| PubMed ID | 24321451 |
| DOI | 10.1186/1750-1172-8-190 |
| Title | Induced pluripotent stem cells from patients with human fibrodysplasia ossificans progressiva show increased mineralization and cartilage formation. |
| Authors | Matsumoto Y, Hayashi Y, Schlieve CR, Ikeya M, Kim H, Nguyen TD, Sami S, Baba S, Barruet E, Nasu A, Asaka I, Otsuka T, Yamanaka S, Conklin BR, Toguchida J, Hsiao EC |
| Journal | Orphanet J Rare Dis |
| Year | 2013 |
| Volume | 8 |
| Issue | - |
| Pages | 190 |
| URL | http://www.ncbi.nlm.nih.gov/pubmed/24321451 |
| Free input | - |
| Note | - |