SKIP000395 |
SKIP ID |
SKIP000395 |
Organism(En) |
- |
Organism(Ja) |
- |
Cell Type(En) |
- |
Cell Type(Ja) |
- |
Cell Tissue(En) |
- |
Cell Tissue(Ja) |
- |
Cell Origin |
Diseased |
Cell Name 1(En) |
AT-iPS-264 |
Cell Name 1(Ja) |
AT-iPS-264 |
Cell Name 2(En) |
- |
Cell Name 2(Ja) |
- |
Disease Name 1(Ja) |
毛細血管拡張性運動失調症 |
ICD Code 1 |
G11.3 |
Disease Name 1(En) |
ataxia telangiectasia |
OMIM1 |
607585 |
Disease Name 2(Ja) |
- |
ICD Code 2 |
- |
Disease Name 2(En) |
- |
OMIM 2 |
- |
Disease Name 3(Ja) |
- |
ICD Code 3 |
- |
Disease Name 3(En) |
- |
OMIM 3 |
- |
Age |
10 |
Age Range |
10-19 |
Sex |
Male |
Race(En) |
Japanese |
Race(Ja) |
Japanese |
Genetic Diagnosis |
Yes |
Not Detected |
No |
Description(En) |
AT1OS-derived iPS cells
|
Description(Ja) |
AT1OS由来iPS細胞
|
Cell Morphology |
human ES-like |
Grade |
Research Grade |
Vector |
Retrovirus |
Transgene |
recombinant retroviruses expressing the four factors(Oct3/4, Sox2, Klf and c-Myc) |
Adhesiveness |
- |
Feeder |
Yes |
Feeder Cell |
irradiated MEFs |
Medium |
Glycotechnica SODATT201 |
Genome Editing |
- |
CO2 |
- |
Mycoplasma |
- |
Detection of Contaminants Mycoplasma |
- |
Pluripotent Markers |
Yes |
Pluripotent Markers Assay |
RT-PCR |
in vitro Differentiation |
Yes |
in vitro Differentiation Assay |
Immunocytochemistry |
in vivo Differentiation |
Yes |
in vivo Differentiation Assay |
Teratoma formation |
Other 1 Assay |
- |
Other 1 Assay Method |
- |
Other 2 Assay |
- |
Other 2 Assay Method |
- |
Other 3 Assay |
- |
Other 3 Assay Method |
- |
Karyotype |
Yes |
Karyotype Assay |
- |
Remaining Vector Detection |
- |
Remaining Vector Detection Assay |
- |
STR |
- |
HLA |
- |
Stem Cell Transcriptome analysis |
- |
Stem Cell Transcriptome analysis Assay |
- |
Author Name(En) |
- |
Author Name(Ja) |
- |
Author Organization(En) |
- |
Author Organization(Ja) |
- |
Author Contact Email |
- |
PI Organization(En) |
National Research Institute for Child Health and Development |
PI Organization(Ja) |
独立行政法人 国立成育医療研究センター研究所 |
PI Name(En) |
Akihiro Umezawa |
PI Name(Ja) |
梅澤 明弘 |
PI Contact Email |
- |
Availability |
Available |
Provider Organization(En) |
National Research Institute for Child Health and Development |
Provider Organization(Ja) |
独立行政法人国立成育医療研究センター研究所 |
Provider Email |
umezawa[at]1985[dot]jukuin[dot]keio[dot]ac[dot]jp |
Provider URL |
- |
Ethical Statement(En) |
- |
Ethical Statement(Ja) |
- |
Terms of Use(En) |
- |
Terms of Use(Ja) |
- |
PubMed ID |
24970375 |
DOI |
10.1038/srep05421 |
Title |
Ataxia telangiectasia derived iPS cells show preserved x-ray sensitivity and decreased chromosomal instability. |
Authors |
Fukawatase Y, Toyoda M, Okamura K, Nakamura K, Nakabayashi K, Takada S, Yamazaki-Inoue M, Masuda A, Nasu M, Hata K, Hanaoka K, Higuchi A, Takubo K, Umezawa A |
Journal |
Sci Rep |
Year |
2014 |
Volume |
4 |
Issue |
- |
Pages |
5421 |
URL |
http://www.ncbi.nlm.nih.gov/pubmed/24970375 |
Free input |
- |
Note |
- |