| SKIP000390 | |
| SKIP ID | SKIP000390 |
| Organism(En) | - |
| Organism(Ja) | - |
| Cell Type(En) | - |
| Cell Type(Ja) | - |
| Cell Tissue(En) | - |
| Cell Tissue(Ja) | - |
| Cell Origin | Diseased |
| Cell Name 1(En) | GM23764 |
| Cell Name 1(Ja) | GM23764 |
| Cell Name 2(En) | - |
| Cell Name 2(Ja) | - |
| Disease Name 1(Ja) | 統合失調症 |
| ICD Code 1 | F209 |
| Disease Name 1(En) | Schizophrenia |
| OMIM1 | 181500 |
| Disease Name 2(Ja) | - |
| ICD Code 2 | - |
| Disease Name 2(En) | - |
| OMIM 2 | - |
| Disease Name 3(Ja) | - |
| ICD Code 3 | - |
| Disease Name 3(En) | - |
| OMIM 3 | - |
| Age | 27 |
| Age Range | 20-29 |
| Sex | Female |
| Race(En) | - |
| Race(Ja) | - |
| Genetic Diagnosis | Yes |
| Not Detected | No |
| Description(En) | Induced pluripotent stem cell line derived from GM02503 fibroblast; passage frozen 23; see GM01490 lymphoid; anorexia nervosa since adolescence; more schizoid than depressed. |
| Description(Ja) | 皮膚線維芽細胞GM02503より人工多能性幹細胞 (iPSC) を樹立。23回継代の凍結サンプル。同一人由来のリンパ球GM01490も参照。青年期から神経性無食欲症を発症。鬱＜統合失調症。 |
| Cell Morphology | human ES-like |
| Grade | Research Grade |
| Vector | Lentivirus |
| Transgene | Oct4, Sox2, Klf4, Myc, Lin28 |
| Adhesiveness | - |
| Feeder | Yes |
| Feeder Cell | CF1 MEFs on 0.1% Gelatin |
| Medium | Knockout DMEM supplemented with 50mg/L basic fibroblast growth factor (bFGF) and 20% knock-out serum replacement (KSR) not inactivated |
| Genome Editing | - |
| CO2 | - |
| Mycoplasma | - |
| Detection of Contaminants Mycoplasma | - |
| Pluripotent Markers | Yes |
| Pluripotent Markers Assay | - |
| in vitro Differentiation | - |
| in vitro Differentiation Assay | - |
| in vivo Differentiation | - |
| in vivo Differentiation Assay | - |
| Other 1 Assay | Yes |
| Other 1 Assay Method | Surface Antigen Expression of Stem Cell Markers (immunostaining) |
| Other 2 Assay | Yes |
| Other 2 Assay Method | Mycoplasma |
| Other 3 Assay | Yes |
| Other 3 Assay Method | Growth on agar |
| Karyotype | Yes |
| Karyotype Assay | - |
| Remaining Vector Detection | - |
| Remaining Vector Detection Assay | - |
| STR | Yes |
| HLA | - |
| Stem Cell Transcriptome analysis | - |
| Stem Cell Transcriptome analysis Assay | - |
| Author Name(En) | Fred H. Gage |
| Author Name(Ja) | フレッド H. ゲイジ |
| Author Organization(En) | Salk Institute for Biological Studies, Laboratory of Genetics |
| Author Organization(Ja) | ソーク研究所 遺伝学研究室 |
| Author Contact Email | - |
| PI Organization(En) | NIGMS Coriell Cell Repository |
| PI Organization(Ja) | NIGMS Coriell Cell Repository |
| PI Name(En) | NIGMS Human Genetic Cell Repository |
| PI Name(Ja) | NIGMS Human Genetic Cell Repository |
| PI Contact Email | - |
| Availability | Available |
| Provider Organization(En) | NIGMS Coriell Cell Repository |
| Provider Organization(Ja) | NIGMS Coriell Cell Repository |
| Provider Email | - |
| Provider URL | http://ccr.coriell.org/Sections/Collections/NIGMS/ipsc_list.aspx?PgId=696 |
| Ethical Statement(En) | - |
| Ethical Statement(Ja) | - |
| Terms of Use(En) | - |
| Terms of Use(Ja) | - |
| PubMed ID | 21490598 |
| DOI | 10.1038/nature09915 |
| Title | Modelling schizophrenia using human induced pluripotent stem cells. |
| Authors | Brennand KJ, Simone A, Jou J, Gelboin-Burkhart C, Tran N, Sangar S, Li Y, Mu Y, Chen G, Yu D, McCarthy S, Sebat J, Gage FH |
| Journal | Nature |
| Year | 2011 |
| Volume | 473 |
| Issue | 7346 |
| Pages | 221-5 |
| URL | http://www.ncbi.nlm.nih.gov/pubmed/21490598 |
| Free input | - |
| Note | - |