| SKIP000842 | |
| SKIP ID | SKIP000842 |
| Organism(En) | - |
| Organism(Ja) | - |
| Cell Type(En) | - |
| Cell Type(Ja) | - |
| Cell Tissue(En) | - |
| Cell Tissue(Ja) | - |
| Cell Origin | Normal |
| Cell Name 1(En) | TFK12(DNAVEC) |
| Cell Name 1(Ja) | TFK12(DNAVEC) |
| Cell Name 2(En) | - |
| Cell Name 2(Ja) | - |
| Disease Name 1(Ja) | - |
| ICD Code 1 | - |
| Disease Name 1(En) | - |
| OMIM1 | - |
| Disease Name 2(Ja) | - |
| ICD Code 2 | - |
| Disease Name 2(En) | - |
| OMIM 2 | - |
| Disease Name 3(Ja) | - |
| ICD Code 3 | - |
| Disease Name 3(En) | - |
| OMIM 3 | - |
| Age | 25 |
| Age Range | 20-29 |
| Sex | Male |
| Race(En) | - |
| Race(Ja) | - |
| Genetic Diagnosis | -- |
| Not Detected | No |
| Description(En) | Induced pluripotent stem cell (iPSC) line derived from peripheral blood cells, T-cells; for reprogramming, sendai viruse vectors, which contained human Oct3/4, Sox2, Klf4 and c-Myc, were used. Healthy iPSC line. |
| Description(Ja) | 血球系細胞（T細胞）にセンダイウイルスベクターを用いてOct3/4, Sox2, Klf4, c-Mycの4因子を導入して樹立したヒト人工多能性幹細胞株（iPSC）。 健常者由来iPS細胞株。 |
| Cell Morphology | human ES-like |
| Grade | Research Grade |
| Vector | Sendai virus |
| Transgene | Sendai Virus (DNAVEC: CytoTuneTM-iPS Cat. No. DV-0301) SeV18+HS-OCT3/4/TS Delta-F SeV18+HS-SOX2/TS Delta-F SeV18+HS-KLF4/TS Delta-F SeV18(HNL)c-MYCQC/TS Delta-F |
| Adhesiveness | - |
| Feeder | Yes |
| Feeder Cell | Mitomycn C-inactivated SNL feeder cells |
| Medium | standard hESC medium (Dulbecco's modified Eagle's medium [DMEM]/F12 [Sigma] containing 20% KnockOut serum replacement [KSR; Life Technologies], nonessential amino acids [NEAA], 0.1 mM 2-mercaptoethanol [Sigma], and 4 ng/ml fibroblast growth factor 2 [FGF-2] [PeproTech]) |
| Genome Editing | - |
| CO2 | - |
| Mycoplasma | Unknown |
| Detection of Contaminants Mycoplasma | - |
| Pluripotent Markers | Yes |
| Pluripotent Markers Assay | ICC |
| in vitro Differentiation | Yes |
| in vitro Differentiation Assay | - |
| in vivo Differentiation | - |
| in vivo Differentiation Assay | - |
| Other 1 Assay | - |
| Other 1 Assay Method | - |
| Other 2 Assay | - |
| Other 2 Assay Method | - |
| Other 3 Assay | - |
| Other 3 Assay Method | - |
| Karyotype | - |
| Karyotype Assay | - |
| Remaining Vector Detection | - |
| Remaining Vector Detection Assay | - |
| STR | - |
| HLA | - |
| Stem Cell Transcriptome analysis | - |
| Stem Cell Transcriptome analysis Assay | - |
| Author Name(En) | Hideyuki Okano |
| Author Name(Ja) | 岡野 栄之 |
| Author Organization(En) | Department of Physiology, Keio University School of Medicine |
| Author Organization(Ja) | 慶應義塾大学 医学部 生理学教室 |
| Author Contact Email | hidokano[at]a2[dot]keio[dot]jp |
| PI Organization(En) | Department of Physiology, Keio University School of Medicine |
| PI Organization(Ja) | 慶應義塾大学 医学部 生理学教室 |
| PI Name(En) | Hideyuki Okano |
| PI Name(Ja) | 岡野 栄之 |
| PI Contact Email | hidokano[at]a2[dot]keio[dot]jp |
| Availability | Information Only |
| Provider Organization(En) | Department of Physiology, Keio University School of Medicine |
| Provider Organization(Ja) | 慶應義塾大学 医学部 生理学教室 |
| Provider Email | - |
| Provider URL | - |
| Ethical Statement(En) | - |
| Ethical Statement(Ja) | - |
| Terms of Use(En) | - |
| Terms of Use(Ja) | - |
| PubMed ID | 26905201 |
| DOI | 10.1016/j.stemcr.2016.01.010 |
| Title | Functional Neurons Generated from T Cell-Derived Induced Pluripotent Stem Cells for Neurological Disease Modeling. |
| Authors | Matsumoto T, Fujimori K, Andoh-Noda T, Ando T, Kuzumaki N, Toyoshima M, Tada H, Imaizumi K, Ishikawa M, Yamaguchi R, Isoda M, Zhou Z, Sato S, Kobayashi T, Ohtaka M, Nishimura K, Kurosawa H, Yoshikawa T, Takahashi T, Nakanishi M, Ohyama M, Hattori N, Akamatsu W, Okano H |
| Journal | Stem Cell Reports |
| Year | 2016 |
| Volume | 6 |
| Issue | 3 |
| Pages | 422-35 |
| URL | http://www.ncbi.nlm.nih.gov/pubmed/26905201 |
| Free input | - |
| Note | - |