SKIP000795 |
SKIP ID |
SKIP000795 |
Organism(En) |
- |
Organism(Ja) |
- |
Cell Type(En) |
- |
Cell Type(Ja) |
- |
Cell Tissue(En) |
- |
Cell Tissue(Ja) |
- |
Cell Origin |
Diseased |
Cell Name 1(En) |
P1 |
Cell Name 1(Ja) |
P1 |
Cell Name 2(En) |
CiRA00070 |
Cell Name 2(Ja) |
CiRA00070 |
Disease Name 1(Ja) |
脊髄性筋萎縮症Ⅰ型 |
ICD Code 1 |
G120 |
Disease Name 1(En) |
SPINAL MUSCULAR ATROPHY I; SMA1 |
OMIM1 |
253300 |
Disease Name 2(Ja) |
- |
ICD Code 2 |
- |
Disease Name 2(En) |
- |
OMIM 2 |
- |
Disease Name 3(Ja) |
- |
ICD Code 3 |
- |
Disease Name 3(En) |
- |
OMIM 3 |
- |
Age |
- |
Age Range |
0-9 |
Sex |
Male |
Race(En) |
- |
Race(Ja) |
- |
Genetic Diagnosis |
Yes |
Not Detected |
No |
Description(En) |
SMA patient(Coriell IDs GM00232 Fibroblast)-derived induced pluripotent stem cells (iPSCs) |
Description(Ja) |
脊髄性筋萎縮症(Coriell GM00232)患者由来のiPS細胞 |
Cell Morphology |
human ES-like |
Grade |
Research Grade |
Vector |
Other |
Transgene |
OCT3/4, SOX2, KLF4, L-MYC, LIN28 and p53 shRNA |
Adhesiveness |
- |
Feeder |
Yes |
Feeder Cell |
SNL or MEF |
Medium |
embryonic stem cell medium (ReproCELL) |
Genome Editing |
- |
CO2 |
- |
Mycoplasma |
- |
Detection of Contaminants Mycoplasma |
- |
Pluripotent Markers |
Yes |
Pluripotent Markers Assay |
Immunocytochemical analysis |
in vitro Differentiation |
Yes |
in vitro Differentiation Assay |
- |
in vivo Differentiation |
Yes |
in vivo Differentiation Assay |
Teratoma formation assay |
Other 1 Assay |
Yes |
Other 1 Assay Method |
q-PCR |
Other 2 Assay |
- |
Other 2 Assay Method |
- |
Other 3 Assay |
- |
Other 3 Assay Method |
- |
Karyotype |
Yes |
Karyotype Assay |
- |
Remaining Vector Detection |
- |
Remaining Vector Detection Assay |
- |
STR |
- |
HLA |
- |
Stem Cell Transcriptome analysis |
- |
Stem Cell Transcriptome analysis Assay |
- |
Author Name(En) |
Megumu K. Saito |
Author Name(Ja) |
齋藤 潤 |
Author Organization(En) |
Department of Clinical Application, Center for iPS Cell Research and Application (CiRA), Kyoto University |
Author Organization(Ja) |
京都大学iPS細胞研究所 |
Author Contact Email |
msaito[at]cira[dot]kyoto-u[dot]ac[dot]jp |
PI Organization(En) |
- |
PI Organization(Ja) |
- |
PI Name(En) |
- |
PI Name(Ja) |
- |
PI Contact Email |
- |
Availability |
Information Only |
Provider Organization(En) |
Department of Clinical Application, Center for iPS Cell Research and Application (CiRA), Kyoto University |
Provider Organization(Ja) |
京都大学iPS細胞研究所 |
Provider Email |
msaito[at]cira[dot]kyoto-u[dot]ac[dot]jp |
Provider URL |
http://www.cira.kyoto-u.ac.jp/nakahata/ |
Ethical Statement(En) |
- |
Ethical Statement(Ja) |
- |
Terms of Use(En) |
- |
Terms of Use(Ja) |
- |
PubMed ID |
25801509 |
DOI |
10.1016/j.stemcr.2015.02.010 |
Title |
Modeling the early phenotype at the neuromuscular junction of spinal muscular atrophy using patient-derived iPSCs. |
Authors |
Yoshida M, Kitaoka S, Egawa N, Yamane M, Ikeda R, Tsukita K, Amano N, Watanabe A, Morimoto M, Takahashi J, Hosoi H, Nakahata T, Inoue H, Saito MK |
Journal |
Stem Cell Reports |
Year |
2015 |
Volume |
4 |
Issue |
4 |
Pages |
561-8 |
URL |
http://www.ncbi.nlm.nih.gov/pubmed/25801509 |
Free input |
- |
Note |
- |