| SKIP000844 | |
| SKIP ID | SKIP000844 |
| Organism(En) | - |
| Organism(Ja) | - |
| Cell Type(En) | - |
| Cell Type(Ja) | - |
| Cell Tissue(En) | - |
| Cell Tissue(Ja) | - |
| Cell Origin | Diseased |
| Cell Name 1(En) | Affected Twin with GBA+/N370S |
| Cell Name 1(Ja) | Aaffected Twin with GBA+/N370S |
| Cell Name 2(En) | 10001.198.01 |
| Cell Name 2(Ja) | 10001.198.01 |
| Disease Name 1(Ja) | パーキンソン病 |
| ICD Code 1 | G20 |
| Disease Name 1(En) | Parkinson Disease |
| OMIM1 | 168600 |
| Disease Name 2(Ja) | - |
| ICD Code 2 | - |
| Disease Name 2(En) | - |
| OMIM 2 | - |
| Disease Name 3(Ja) | - |
| ICD Code 3 | - |
| Disease Name 3(En) | - |
| OMIM 3 | - |
| Age | 68 |
| Age Range | 60-69 |
| Sex | Male |
| Race(En) | Ashkenazi Jewish |
| Race(Ja) | Ashkenazi Jewish |
| Genetic Diagnosis | Yes |
| Not Detected | No |
| Description(En) | Transgene-free iPS cells from Parkinson Disease patient who has Monozygotic twin brother. Using CytoTune iPS Sendai reprogramming protocol (Life Technologies). |
| Description(Ja) | 一卵性双生児のパーキンソン病患者由来iPS細胞。一方は発病していない。 |
| Cell Morphology | human ES-like |
| Grade | Research Grade |
| Vector | Sendai virus |
| Transgene | Oct4, Sox2,Klf4, and c-Myc |
| Adhesiveness | - |
| Feeder | Yes |
| Feeder Cell | MEF |
| Medium | HuESM |
| Genome Editing | - |
| CO2 | - |
| Mycoplasma | - |
| Detection of Contaminants Mycoplasma | - |
| Pluripotent Markers | Yes |
| Pluripotent Markers Assay | Immunostaining |
| in vitro Differentiation | Yes |
| in vitro Differentiation Assay | EB fromation |
| in vivo Differentiation | - |
| in vivo Differentiation Assay | - |
| Other 1 Assay | Yes |
| Other 1 Assay Method | - |
| Other 2 Assay | - |
| Other 2 Assay Method | - |
| Other 3 Assay | - |
| Other 3 Assay Method | - |
| Karyotype | - |
| Karyotype Assay | - |
| Remaining Vector Detection | - |
| Remaining Vector Detection Assay | - |
| STR | - |
| HLA | - |
| Stem Cell Transcriptome analysis | - |
| Stem Cell Transcriptome analysis Assay | - |
| Author Name(En) | Chris M. Woodard |
| Author Name(Ja) | Chris M. Woodard |
| Author Organization(En) | The New York Stem Cell Foundation Research Institute |
| Author Organization(Ja) | The New York Stem Cell Foundation Research Institute |
| Author Contact Email | - |
| PI Organization(En) | Scott A. Noggle |
| PI Organization(Ja) | Scott A. Noggle |
| PI Name(En) | The New York Stem Cell Foundation Research Institute |
| PI Name(Ja) | The New York Stem Cell Foundation Research Institute |
| PI Contact Email | snoggle[at]nyscf[dot]org |
| Availability | Information Only |
| Provider Organization(En) | - |
| Provider Organization(Ja) | - |
| Provider Email | - |
| Provider URL | - |
| Ethical Statement(En) | - |
| Ethical Statement(Ja) | - |
| Terms of Use(En) | - |
| Terms of Use(Ja) | - |
| PubMed ID | 25456120 |
| DOI | 10.1016/j.celrep.2014.10.023 |
| Title | iPSC-derived dopamine neurons reveal differences between monozygotic twins discordant for Parkinson's disease. |
| Authors | Woodard CM, Campos BA, Kuo SH, Nirenberg MJ, Nestor MW, Zimmer M, Mosharov EV, Sulzer D, Zhou H, Paull D, Clark L, Schadt EE, Sardi SP, Rubin L, Eggan K, Brock M, Lipnick S, Rao M, Chang S, Li A, Noggle SA |
| Journal | Cell Rep |
| Year | 2014 |
| Volume | 9 |
| Issue | 4 |
| Pages | 1173-82 |
| URL | http://www.ncbi.nlm.nih.gov/pubmed/25456120 |
| Free input | - |
| Note | - |