| SKIP000579 | |
| SKIP ID | SKIP000579 |
| Organism(En) | - |
| Organism(Ja) | - |
| Cell Type(En) | - |
| Cell Type(Ja) | - |
| Cell Tissue(En) | - |
| Cell Tissue(Ja) | - |
| Cell Origin | Normal |
| Cell Name 1(En) | iPS 4F16 |
| Cell Name 1(Ja) | iPS 4F16 |
| Cell Name 2(En) | - |
| Cell Name 2(Ja) | - |
| Disease Name 1(Ja) | - |
| ICD Code 1 | - |
| Disease Name 1(En) | - |
| OMIM1 | - |
| Disease Name 2(Ja) | - |
| ICD Code 2 | - |
| Disease Name 2(En) | - |
| OMIM 2 | - |
| Disease Name 3(Ja) | - |
| ICD Code 3 | - |
| Disease Name 3(En) | - |
| OMIM 3 | - |
| Age | - |
| Age Range | -- |
| Sex | -- |
| Race(En) | - |
| Race(Ja) | - |
| Genetic Diagnosis | -- |
| Not Detected | No |
| Description(En) | iPS cell lines were generated from dermal fibroblasts obtained from healthy subject by using four classic retroviral vectors pMXs-Oct4, pMXs-Sox2, pMXs-Klf4, and pMXs-c-Myc encoding (mouse) reprogramming factors. |
| Description(Ja) | 健常人の皮膚細胞から4つのレトロウイルスベクター（pMXs-Oct4, pMXs-Sox2, pMXs-Klf4, and pMXs-c-Myc)を用いてiPS細胞を樹立した。 |
| Cell Morphology | human ES-like |
| Grade | Research Grade |
| Vector | Retrovirus |
| Transgene | pMXs-Oct4, pMXs-Sox2, pMXs-Klf4, and pMXs-c-Myc |
| Adhesiveness | - |
| Feeder | Yes |
| Feeder Cell | mouse embryonic fibroblast (MEF) |
| Medium | the standard hES cell medium (80% DMEM/F12, 20% KO Serum Replacement (Invitrogen) with 4 ng/ml basic fibroblast growth factor) |
| Genome Editing | - |
| CO2 | - |
| Mycoplasma | - |
| Detection of Contaminants Mycoplasma | - |
| Pluripotent Markers | Yes |
| Pluripotent Markers Assay | - |
| in vitro Differentiation | No |
| in vitro Differentiation Assay | - |
| in vivo Differentiation | Yes |
| in vivo Differentiation Assay | teratoma formation |
| Other 1 Assay | - |
| Other 1 Assay Method | - |
| Other 2 Assay | - |
| Other 2 Assay Method | - |
| Other 3 Assay | - |
| Other 3 Assay Method | - |
| Karyotype | No |
| Karyotype Assay | - |
| Remaining Vector Detection | - |
| Remaining Vector Detection Assay | - |
| STR | - |
| HLA | - |
| Stem Cell Transcriptome analysis | - |
| Stem Cell Transcriptome analysis Assay | - |
| Author Name(En) | - |
| Author Name(Ja) | - |
| Author Organization(En) | - |
| Author Organization(Ja) | - |
| Author Contact Email | - |
| PI Organization(En) | Department of Cardiology,Keio University School of Medicine |
| PI Organization(Ja) | 慶應義塾大学医学部循環器内科 |
| PI Name(En) | Shinsuke Yuasa |
| PI Name(Ja) | 湯浅 慎介 |
| PI Contact Email | - |
| Availability | Information Only |
| Provider Organization(En) | - |
| Provider Organization(Ja) | - |
| Provider Email | - |
| Provider URL | - |
| Ethical Statement(En) | - |
| Ethical Statement(Ja) | - |
| Terms of Use(En) | - |
| Terms of Use(Ja) | - |
| PubMed ID | 25389285 |
| DOI | 10.1161/JAHA.114.001263 |
| Title | Endothelin-1 induces myofibrillar disarray and contractile vector variability in hypertrophic cardiomyopathy-induced pluripotent stem cell-derived cardiomyocytes. |
| Authors | Tanaka A, Yuasa S, Mearini G, Egashira T, Seki T, Kodaira M, Kusumoto D, Kuroda Y, Okata S, Suzuki T, Inohara T, Arimura T, Makino S, Kimura K, Kimura A, Furukawa T, Carrier L, Node K, Fukuda K |
| Journal | J Am Heart Assoc |
| Year | 2014 |
| Volume | 3 |
| Issue | 6 |
| Pages | - |
| URL | http://www.ncbi.nlm.nih.gov/pubmed/25389285 |
| Free input | - |
| Note | - |