| SKIP000766 | |
| SKIP ID | SKIP000766 |
| Organism(En) | - |
| Organism(Ja) | - |
| Cell Type(En) | - |
| Cell Type(Ja) | - |
| Cell Tissue(En) | - |
| Cell Tissue(Ja) | - |
| Cell Origin | Diseased |
| Cell Name 1(En) | ARVC-iPSC |
| Cell Name 1(Ja) | ARVC-iPSC |
| Cell Name 2(En) | - |
| Cell Name 2(Ja) | - |
| Disease Name 1(Ja) | 不整脈源性右室心筋症 |
| ICD Code 1 | I428 |
| Disease Name 1(En) | arrhythmogenic right ventricular cardiomyopathy |
| OMIM1 | 609040 |
| Disease Name 2(Ja) | - |
| ICD Code 2 | - |
| Disease Name 2(En) | - |
| OMIM 2 | - |
| Disease Name 3(Ja) | - |
| ICD Code 3 | - |
| Disease Name 3(En) | - |
| OMIM 3 | - |
| Age | 30 |
| Age Range | 30-39 |
| Sex | Male |
| Race(En) | Chinese |
| Race(Ja) | - |
| Genetic Diagnosis | Yes |
| Not Detected | No |
| Description(En) | Disease specific iPS cell from ARVC. |
| Description(Ja) | 不整脈源性右室心筋症患者由来iPS細胞 |
| Cell Morphology | human ES-like |
| Grade | Research Grade |
| Vector | Retrovirus |
| Transgene | SOX2, OCT3/4, KLF4, and C-MYC |
| Adhesiveness | - |
| Feeder | Yes |
| Feeder Cell | - |
| Medium | 80% Knockout DMEM, 20% serum replacement, 1% non-essential amino acid, 1 mM L-glutamine, 0.1 mM β-mercaptoebthanol and 10 ng/ml basic fibroblast growth factor. |
| Genome Editing | - |
| CO2 | 5% |
| Mycoplasma | Unknown |
| Detection of Contaminants Mycoplasma | - |
| Pluripotent Markers | Yes |
| Pluripotent Markers Assay | Immunostaining |
| in vitro Differentiation | Yes |
| in vitro Differentiation Assay | cardiomyocyte differentiation |
| in vivo Differentiation | Yes |
| in vivo Differentiation Assay | Teratoma formation |
| Other 1 Assay | - |
| Other 1 Assay Method | - |
| Other 2 Assay | Yes |
| Other 2 Assay Method | cardiac electrophysiology |
| Other 3 Assay | - |
| Other 3 Assay Method | - |
| Karyotype | No |
| Karyotype Assay | - |
| Remaining Vector Detection | Yes |
| Remaining Vector Detection Assay | - |
| STR | No |
| HLA | No |
| Stem Cell Transcriptome analysis | No |
| Stem Cell Transcriptome analysis Assay | - |
| Author Name(En) | Dongrui Ma |
| Author Name(Ja) | Dongrui Ma |
| Author Organization(En) | Research and Development Unit (RDU), National Heart Centre |
| Author Organization(Ja) | Research and Development Unit (RDU), National Heart Centre |
| Author Contact Email | reginald[dot]liew[dot]k[dot]c[at]nhcs[dot]com[dot]sg |
| PI Organization(En) | Research and Development Unit (RDU), National Heart Centre |
| PI Organization(Ja) | Research and Development Unit (RDU), National Heart Centre |
| PI Name(En) | Reginald Liew |
| PI Name(Ja) | Reginald Liew |
| PI Contact Email | reginald[dot]liew[dot]k[dot]c[at]nhcs[dot]com[dot]sg |
| Availability | Information Only |
| Provider Organization(En) | - |
| Provider Organization(Ja) | - |
| Provider Email | - |
| Provider URL | - |
| Ethical Statement(En) | - |
| Ethical Statement(Ja) | - |
| Terms of Use(En) | - |
| Terms of Use(Ja) | - |
| PubMed ID | 22798562 |
| DOI | 10.1093/eurheartj/ehs226 |
| Title | Generation of patient-specific induced pluripotent stem cell-derived cardiomyocytes as a cellular model of arrhythmogenic right ventricular cardiomyopathy. |
| Authors | Ma D, Wei H, Lu J, Ho S, Zhang G, Sun X, Oh Y, Tan SH, Ng ML, Shim W, Wong P, Liew R |
| Journal | Eur Heart J |
| Year | 2012 |
| Volume | 34 |
| Issue | 15 |
| Pages | 1122-33 |
| URL | http://www.ncbi.nlm.nih.gov/pubmed/22798562 |
| Free input | - |
| Note | - |