SKIP001110
SKIP ID SKIP001110
Organism(En) -
Organism(Ja) -
Cell Type(En) -
Cell Type(Ja) -
Cell Tissue(En) -
Cell Tissue(Ja) -
Cell Origin Normal
Cell Name 1(En) C1-2
Cell Name 1(Ja) C1-2
Cell Name 2(En) -
Cell Name 2(Ja) -
Disease Name 1(Ja) -
ICD Code 1 -
Disease Name 1(En) -
OMIM1 -
Disease Name 2(Ja) -
ICD Code 2 -
Disease Name 2(En) -
OMIM 2 -
Disease Name 3(Ja) -
ICD Code 3 -
Disease Name 3(En) -
OMIM 3 -
Age -
Age Range 0-9
Sex Male
Race(En) -
Race(Ja) -
Genetic Diagnosis --
Not Detected No
Description(En) iPS cells from fibroblasts a control individual outside of the pedigree as an additional control (ATCC(CRL-2097))
Description(Ja) 血縁関係のない正常な個人由来のiPS細胞(コントロール)
Cell Morphology human ES-like
Grade Research Grade
Vector Plasmid
Transgene OCT4,SOX2,KLF4,c-MYC,LIN28,SV40LT.
pEP4 EO2S ET2K (Addgene Plasmid 20927), pEP4 EO2S EN2L (Addgene Plasmid 20922), and pEP4 EO2S EM2K (Addgene Plasmid 20923)
Adhesiveness -
Feeder Yes
Feeder Cell MEF
Medium D-MEM/F12 (Invitrogen), 20% Knockout Serum Replacement (KSR, Invitrogen), 2 mM l-glutamine (Invitrogen), 100 uM MEM NEAA (Invitrogen), 100 uM β-mercaptoethanol (Invitrogen), and 10 ng ml-1 human basic FGF (bFGF, PeproTech)
Genome Editing -
CO2 -
Mycoplasma -
Detection of Contaminants Mycoplasma -
Pluripotent Markers Yes
Pluripotent Markers Assay Immunostaining
in vitro Differentiation Yes
in vitro Differentiation Assay Embryoid body assay
in vivo Differentiation Yes
in vivo Differentiation Assay Teratoma formation
Other 1 Assay Yes
Other 1 Assay Method Differentiation of iPS cells into forebrain-specific neural progenitors and cortical neurons
Other 2 Assay -
Other 2 Assay Method -
Other 3 Assay -
Other 3 Assay Method -
Karyotype Yes
Karyotype Assay G-banding
Remaining Vector Detection -
Remaining Vector Detection Assay -
STR -
HLA -
Stem Cell Transcriptome analysis -
Stem Cell Transcriptome analysis Assay -
Author Name(En) -
Author Name(Ja) -
Author Organization(En) -
Author Organization(Ja) -
Author Contact Email -
PI Organization(En) Johns Hopkins University School of Medicine
PI Organization(Ja) ジョンスホプキンス大学
PI Name(En) Hongjun Song
PI Name(Ja) 宋红军
PI Contact Email -
Availability Information Only
Provider Organization(En) -
Provider Organization(Ja) -
Provider Email -
Provider URL -
Ethical Statement(En) -
Ethical Statement(Ja) -
Terms of Use(En) -
Terms of Use(Ja) -
PubMed ID 25132547
DOI 10.1038/nature13716
Title Synaptic dysregulation in a human iPS cell model of mental disorders.
Authors Wen Z, Nguyen HN, Guo Z, Lalli MA, Wang X, Su Y, Kim NS, Yoon KJ, Shin J, Zhang C, Makri G, Nauen D, Yu H, Guzman E, Chiang CH, Yoritomo N, Kaibuchi K, Zou J, Christian KM, Cheng L, Ross CA, Margolis RL, Chen G, Kosik KS, Song H, Ming GL
Journal Nature
Year 2014
Volume 515
Issue 7527
Pages 414-8
URL -
Free input -
Note -