SKIP000838
SKIP ID SKIP000838
Organism(En) -
Organism(Ja) -
Cell Type(En) -
Cell Type(Ja) -
Cell Tissue(En) -
Cell Tissue(Ja) -
Cell Origin Diseased
Cell Name 1(En) TPB27 (DNAVEC)
Cell Name 1(Ja) TPB27 (DNAVEC)
Cell Name 2(En) -
Cell Name 2(Ja) -
Disease Name 1(Ja) 家族性パーキンソン病
ICD Code 1 -
Disease Name 1(En) G20
OMIM1 -
Disease Name 2(Ja) -
ICD Code 2 -
Disease Name 2(En) -
OMIM 2 -
Disease Name 3(Ja) -
ICD Code 3 -
Disease Name 3(En) -
OMIM 3 -
Age -
Age Range 50-59
Sex Male
Race(En) -
Race(Ja) -
Genetic Diagnosis Yes
Not Detected No
Description(En) TPB27(DNAVEC) is iPSC line reprogrammed from a Parkinson disease patient's T-cells, which deleated exon 6 and 7 in parkin gene.
"DNAVEC": SeV vectors, which were produced by DNAVEC Corp.(Cytotune).
Description(Ja) パーキンソン病患者T細胞より樹立したiPS細胞株。
parkin遺伝子のExon 6,7欠失。
"DNAVEC"はDNAVEC社のセンダイウイルスベクターキット(cytotune)を意味している。
Cell Morphology human ES-like
Grade Research Grade
Vector Sendai virus
Transgene Human OCT3/4, SOX2, KLF4, and c-MYC
Adhesiveness -
Feeder Yes
Feeder Cell SNL 76/7
Medium Primate ES Cell Medium+4ng/mL human basic FGF
Genome Editing -
CO2 3%
Mycoplasma -
Detection of Contaminants Mycoplasma -
Pluripotent Markers Yes
Pluripotent Markers Assay ICC
in vitro Differentiation Yes
in vitro Differentiation Assay neural differentiation
in vivo Differentiation -
in vivo Differentiation Assay -
Other 1 Assay -
Other 1 Assay Method -
Other 2 Assay -
Other 2 Assay Method -
Other 3 Assay -
Other 3 Assay Method -
Karyotype No
Karyotype Assay -
Remaining Vector Detection -
Remaining Vector Detection Assay -
STR -
HLA -
Stem Cell Transcriptome analysis -
Stem Cell Transcriptome analysis Assay -
Author Name(En) Hideyuki Okano
Author Name(Ja) 岡野栄之
Author Organization(En) Keio University, School of Medicine, Department of Physiology
Author Organization(Ja) 慶應義塾大学 医学部 生理学教室
Author Contact Email hidokano[at]a2[dot]keio[dot]jp
PI Organization(En) Keio University, School of Medicine, Department of Physiology
PI Organization(Ja) 慶應義塾大学 医学部 生理学教室
PI Name(En) Hideyuki Okano
PI Name(Ja) 岡野栄之
PI Contact Email hidokano[at]a2[dot]keio[dot]jp
Availability Information Only
Provider Organization(En) Keio University, School of Medicine, Department of Physiology
Provider Organization(Ja) 慶應義塾大学 医学部 生理学教室
Provider Email -
Provider URL -
Ethical Statement(En) -
Ethical Statement(Ja) -
Terms of Use(En) -
Terms of Use(Ja) -
PubMed ID 26905201
DOI 10.1016/j.stemcr.2016.01.010
Title Functional Neurons Generated from T Cell-Derived Induced Pluripotent Stem Cells for Neurological Disease Modeling.
Authors Matsumoto T, Fujimori K, Andoh-Noda T, Ando T, Kuzumaki N, Toyoshima M, Tada H, Imaizumi K, Ishikawa M, Yamaguchi R, Isoda M, Zhou Z, Sato S, Kobayashi T, Ohtaka M, Nishimura K, Kurosawa H, Yoshikawa T, Takahashi T, Nakanishi M, Ohyama M, Hattori N, Akamatsu W, Okano H
Journal Stem Cell Reports
Year 2016
Volume 6
Issue 3
Pages 422-35
URL http://www.ncbi.nlm.nih.gov/pubmed/26905201
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