SKIP000182
SKIP ID SKIP000182
Organism(En) -
Organism(Ja) -
Cell Type(En) -
Cell Type(Ja) -
Cell Tissue(En) -
Cell Tissue(Ja) -
Cell Origin Diseased
Cell Name 1(En) GM23226
Cell Name 1(Ja) GM23226
Cell Name 2(En) -
Cell Name 2(Ja) -
Disease Name 1(Ja) 1型糖尿病
ICD Code 1 E10
Disease Name 1(En) diabetes (mellitus), juvenile-onset
OMIM1 222100
Disease Name 2(Ja) -
ICD Code 2 -
Disease Name 2(En) -
OMIM 2 -
Disease Name 3(Ja) -
ICD Code 3 -
Disease Name 3(En) -
OMIM 3 -
Age 42
Age Range 40-49
Sex Female
Race(En) American Indian
Race(Ja) American Indian
Genetic Diagnosis Yes
Not Detected No
Description(En) iPSCs derived from GM02416 Fibroblast. Multifactorial Defect
Description(Ja) 遺伝性若年発症I型糖尿病患者線維芽細胞(GM02416)由来iPS細胞 多因子の異常
Cell Morphology human ES-like
Grade --
Vector Retrovirus
Transgene Oct4, Sox2, Klf-4, c-Myc, retroviral vector
Adhesiveness Yes
Feeder Yes
Feeder Cell CF1 MEFs on 0.1% Gelatin
Medium Ham's F12 Medium/Dulbecco Modified Eagles Medium, 1:1 mixture with 2mM L-glutamine
Genome Editing -
CO2 -
Mycoplasma -
Detection of Contaminants Mycoplasma -
Pluripotent Markers -
Pluripotent Markers Assay -
in vitro Differentiation -
in vitro Differentiation Assay -
in vivo Differentiation -
in vivo Differentiation Assay -
Other 1 Assay -
Other 1 Assay Method -
Other 2 Assay -
Other 2 Assay Method -
Other 3 Assay -
Other 3 Assay Method -
Karyotype Yes
Karyotype Assay 46,XX.arr(1-22,X)x2
Remaining Vector Detection -
Remaining Vector Detection Assay -
STR -
HLA -
Stem Cell Transcriptome analysis -
Stem Cell Transcriptome analysis Assay -
Author Name(En) George Q Daley
Author Name(Ja) George Q Daley
Author Organization(En) Harvard Stem Cell Institute
Author Organization(Ja) Harvard Stem Cell Institute
Author Contact Email -
PI Organization(En) -
PI Organization(Ja) -
PI Name(En) -
PI Name(Ja) -
PI Contact Email -
Availability Available
Provider Organization(En) NIGMS Coriell Cell Repository
Provider Organization(Ja) NIGMS Coriell Cell Repository
Provider Email -
Provider URL http://ccr.coriell.org/Sections/Collections/NIGMS/ipsc_list.aspx?PgId=696
Ethical Statement(En) -
Ethical Statement(Ja) -
Terms of Use(En) -
Terms of Use(Ja) -
PubMed ID 18691744
DOI 10.1016/j.cell.2008.07.041
Title Disease-Specific Induced Pluripotent Stem Cells
Authors Park IH, Arora N, Huo H, Maherali N, Ahfeldt T, Shimamura A, Lensch MW, Cowan C, Hochedlinger K, Daley GQ
Journal Cell
Year 2008
Volume 34
Issue 5
Pages 877-86
URL http://www.ncbi.nlm.nih.gov/pubmed/?term=18691744
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