| SKIP000184 | |
| SKIP ID | SKIP000184 |
| Organism(En) | - |
| Organism(Ja) | - |
| Cell Type(En) | - |
| Cell Type(Ja) | - |
| Cell Tissue(En) | - |
| Cell Tissue(Ja) | - |
| Cell Origin | Diseased |
| Cell Name 1(En) | GM23232 |
| Cell Name 1(Ja) | GM23232 |
| Cell Name 2(En) | - |
| Cell Name 2(Ja) | - |
| Disease Name 1(Ja) | ADA欠乏症 |
| ICD Code 1 | D813 |
| Disease Name 1(En) | Adenosine deaminase [ADA] deficiency |
| OMIM1 | 102700 |
| Disease Name 2(Ja) | - |
| ICD Code 2 | - |
| Disease Name 2(En) | - |
| OMIM 2 | - |
| Disease Name 3(Ja) | - |
| ICD Code 3 | - |
| Disease Name 3(En) | - |
| OMIM 3 | - |
| Age | - |
| Age Range | 0-9 |
| Sex | Male |
| Race(En) | - |
| Race(Ja) | - |
| Genetic Diagnosis | Yes |
| Not Detected | No |
| Description(En) | iPSCs derived from GM01390 Fibroblast. T cell negtive, B cell negative, NK cell negtive, due to adenosine deaminase deficiency |
| Description(Ja) | adenosine deaminase 欠損患者線維芽細胞（GM01390) 由来。常染色体劣性adenosine deaminase 欠失。患者は重度の免疫不全、T細胞、B細胞、NK細胞陰性。 |
| Cell Morphology | human ES-like |
| Grade | -- |
| Vector | Retrovirus |
| Transgene | Oct4, Sox2, Klf-4, c-Myc, retroviral vector |
| Adhesiveness | Yes |
| Feeder | Yes |
| Feeder Cell | CF1 MEFs on 0.1% Gelatin |
| Medium | Ham's F12 Medium/Dulbecco Modified Eagles Medium, 1:1 mixture with 2mM L-glutamine |
| Genome Editing | - |
| CO2 | - |
| Mycoplasma | - |
| Detection of Contaminants Mycoplasma | - |
| Pluripotent Markers | - |
| Pluripotent Markers Assay | - |
| in vitro Differentiation | - |
| in vitro Differentiation Assay | - |
| in vivo Differentiation | - |
| in vivo Differentiation Assay | - |
| Other 1 Assay | - |
| Other 1 Assay Method | - |
| Other 2 Assay | - |
| Other 2 Assay Method | - |
| Other 3 Assay | - |
| Other 3 Assay Method | - |
| Karyotype | Yes |
| Karyotype Assay | 46,XY.arr(1-22)x2,(XY)x1 |
| Remaining Vector Detection | - |
| Remaining Vector Detection Assay | - |
| STR | - |
| HLA | - |
| Stem Cell Transcriptome analysis | - |
| Stem Cell Transcriptome analysis Assay | - |
| Author Name(En) | George Q Daley |
| Author Name(Ja) | George Q Daley |
| Author Organization(En) | Harvard Stem Cell Institute |
| Author Organization(Ja) | Harvard Stem Cell Institute |
| Author Contact Email | - |
| PI Organization(En) | - |
| PI Organization(Ja) | - |
| PI Name(En) | - |
| PI Name(Ja) | - |
| PI Contact Email | - |
| Availability | Available |
| Provider Organization(En) | NIGMS Coriell Cell Repository |
| Provider Organization(Ja) | NIGMS Coriell Cell Repository |
| Provider Email | - |
| Provider URL | http://ccr.coriell.org/Sections/Collections/NIGMS/ipsc_list.aspx?PgId=696 |
| Ethical Statement(En) | - |
| Ethical Statement(Ja) | - |
| Terms of Use(En) | - |
| Terms of Use(Ja) | - |
| PubMed ID | 18691744 |
| DOI | 10.1016/j.cell.2008.07.041 |
| Title | Disease-Specific Induced Pluripotent Stem Cells |
| Authors | Park IH, Arora N, Huo H, Maherali N, Ahfeldt T, Shimamura A, Lensch MW, Cowan C, Hochedlinger K, Daley GQ |
| Journal | Cell |
| Year | 2008 |
| Volume | 34 |
| Issue | 5 |
| Pages | 877-86 |
| URL | http://www.ncbi.nlm.nih.gov/pubmed/?term=18691744 |
| Free input | - |
| Note | - |