| 1689 | |
| Entry | 1689 | 
| Residue(mutation) | - | 
| Residue | Wild | 
| Functionally important | yes | 
| Function of the protein | drug transport; inter-domain communication | 
| Location | - | 
| Protein Name(abbreviation) | Multidrug transporter, P-glycoprotein | 
| Source(scientific name) | Homo sapiens | 
| Source(english name) | Human | 
| Authors | Storm J, O'Mara ML, Crowley EH, Peall J, Tieleman DP, Kerr ID, Callaghan R | 
| Journal Reference | Biochemistry. 2007 Sep 4;46(35):9899-910 | 
| PMID | 17696319 | 
| Experiments | Calorimetric assay | 
| Experimental data | 3.4 | 
| Parameter | fold stimulation | 
| Methods/conditions | Nicardipine | 
| PDB ID | - | 
| ASA | - | 
| Sec. Str | - | 
| Uniprot ID | MDR1_HUMAN (P08183) | 
| Type | Helix | 
| Remarks | - | 
| Keywords | inter-domain communication; drug transport; substrate translocation; ATPase activity |