| 1703 | |
| Entry | 1703 |
| Residue(mutation) | G360C |
| Residue | - |
| Functionally important | yes |
| Function of the protein | drug transport; inter-domain communication |
| Location | TM6 |
| Protein Name(abbreviation) | Multidrug transporter, P-glycoprotein |
| Source(scientific name) | Homo sapiens |
| Source(english name) | Human |
| Authors | Storm J, O'Mara ML, Crowley EH, Peall J, Tieleman DP, Kerr ID, Callaghan R |
| Journal Reference | Biochemistry. 2007 Sep 4;46(35):9899-910 |
| PMID | 17696319 |
| Experiments | Calorimetric assay |
| Experimental data | 5.9 |
| Parameter | EC50 (microM) |
| Methods/conditions | Vinblastine |
| PDB ID | - |
| ASA | - |
| Sec. Str | - |
| Uniprot ID | MDR1_HUMAN (P08183) |
| Type | Helix |
| Remarks | - |
| Keywords | inter-domain communication; drug transport; substrate translocation; ATPase activity |