| 1776 | |
| Entry | 1776 |
| Residue(mutation) | - |
| Residue | Wild |
| Functionally important | yes |
| Function of the protein | Receptor-G protein coupling |
| Location | - |
| Protein Name(abbreviation) | M3 muscarinic acetylcholine receptor |
| Source(scientific name) | Rattus norvegicus |
| Source(english name) | Rat |
| Authors | Li JH, Hamdan FF, Kim SK, Jacobson KA, Zhang X, Han SJ, Wess J. |
| Journal Reference | Biochemistry. 2008 Mar 4;47(9):2776-88. |
| PMID | 18247581 |
| Experiments | site directed mutagenesis; Disulfide cross-linking |
| Experimental data | 24 |
| Parameter | EC50 (nm) |
| Methods/conditions | Carbachol-induced IP production |
| PDB ID | 2CSA |
| ASA | - |
| Sec. Str | - |
| Uniprot ID | ACM3_RAT (P08483) |
| Type | Helix |
| Remarks | - |
| Keywords | conformational change; disulfide cross linking; GPCR; Cys mutant |