225 |
Entry |
225 |
Residue(mutation) |
- |
Residue |
Wild |
Functionally important |
- |
Function of the protein |
- |
Location |
- |
Protein Name(abbreviation) |
Multidrug resistance protein 1; MRP1 |
Source(scientific name) |
Homo sapiens |
Source(english name) |
Human |
Authors |
Yang Y, Chen Q, Zhang JT |
Journal Reference |
J Biol Chem. 2002 Nov 15;277(46):44268-77 |
PMID |
12235150 |
Experiments |
mutagenesis |
Experimental data |
89 |
Parameter |
Vmax (pmol/mg/min) |
Methods/conditions |
rapid filtration method; scintillation counting |
PDB ID |
2cbz |
ASA |
- |
Sec. Str |
- |
Uniprot ID |
MRP1_HUMAN (P33527) |
Type |
Helix |
Remarks |
conformational change |
Keywords |
ATP binding; mutation; conformational change; cysteine |