2257
Entry 2257
Residue(mutation) I178C
Residue -
Functionally important -
Function of the protein translocation pathway
Location TM4
Protein Name(abbreviation) Bile Acid transporter
Source(scientific name) Homo sapiens
Source(english name) Human
Authors Khantwal CM, Swaan PW
Journal Reference Biochemistry. 2008 Mar 25;47(12):3606-14
PMID 18311924
Experiments Cysteine-scanning mutagenesis
Experimental data 80
Parameter uptake activity (%)
Methods/conditions TCA
PDB ID -
ASA -
Sec. Str -
Uniprot ID NTCP2_HUMAN (Q12908)
Type Helix
Remarks TCA; taurocholic acid
Keywords cysteine-scanning mutagenesis; transport; uptake; charged; polar; sodium translocation