2261
Entry 2261
Residue(mutation) D163C
Residue -
Functionally important -
Function of the protein translocation pathway
Location TM4
Protein Name(abbreviation) Bile Acid transporter
Source(scientific name) Homo sapiens
Source(english name) Human
Authors Khantwal CM, Swaan PW
Journal Reference Biochemistry. 2008 Mar 25;47(12):3606-14
PMID 18311924
Experiments Cysteine-scanning mutagenesis
Experimental data 105
Parameter uptake activity (%)
Methods/conditions MTSES
PDB ID -
ASA -
Sec. Str -
Uniprot ID NTCP2_HUMAN (Q12908)
Type Helix
Remarks MTSES; sodium(2-sulfonatoethyl)methanethiosulfonate
Keywords cysteine-scanning mutagenesis; transport; uptake; charged; polar; sodium translocation