2281 |
Entry |
2281 |
Residue(mutation) |
T167C |
Residue |
- |
Functionally important |
- |
Function of the protein |
translocation pathway |
Location |
TM4 |
Protein Name(abbreviation) |
Bile Acid transporter |
Source(scientific name) |
Homo sapiens |
Source(english name) |
Human |
Authors |
Khantwal CM, Swaan PW |
Journal Reference |
Biochemistry. 2008 Mar 25;47(12):3606-14 |
PMID |
18311924 |
Experiments |
Cysteine-scanning mutagenesis |
Experimental data |
103 |
Parameter |
uptake activity (%) |
Methods/conditions |
MTSET |
PDB ID |
- |
ASA |
- |
Sec. Str |
- |
Uniprot ID |
NTCP2_HUMAN (Q12908) |
Type |
Helix |
Remarks |
METSTE; [2-(trimethylammonium)etyl]methanethiosulfonate bromide |
Keywords |
cysteine-scanning mutagenesis; transport; uptake; charged; polar; sodium translocation |