2324
Entry 2324
Residue(mutation) T220S
Residue -
Functionally important -
Function of the protein transport
Location -
Protein Name(abbreviation) Organic cation transporter PMAT
Source(scientific name) Homo sapiens
Source(english name) Human
Authors Zhou M, Xia L, Engel K, Wang J
Journal Reference J Biol Chem. 2007 Feb 2;282(5):3188-98
PMID 17121826
Experiments Mutagenesis
Experimental data 58
Parameter Km (%)
Methods/conditions Dopamine
PDB ID -
ASA -
Sec. Str -
Uniprot ID S29A4_HUMAN (Q7RTT9)
Type Helix
Remarks -
Keywords cation transporter; substrate selectivity; alanine mutants; PMAT activity; Helical wheel analysis