2326 |
Entry |
2326 |
Residue(mutation) |
T220A |
Residue |
- |
Functionally important |
- |
Function of the protein |
transport |
Location |
- |
Protein Name(abbreviation) |
Organic cation transporter PMAT |
Source(scientific name) |
Homo sapiens |
Source(english name) |
Human |
Authors |
Zhou M, Xia L, Engel K, Wang J |
Journal Reference |
J Biol Chem. 2007 Feb 2;282(5):3188-97 |
PMID |
17121826 |
Experiments |
Mutagenesis |
Experimental data |
21 |
Parameter |
Vmax (%) |
Methods/conditions |
Dopamine |
PDB ID |
- |
ASA |
- |
Sec. Str |
- |
Uniprot ID |
S29A4_HUMAN (Q7RTT9) |
Type |
Helix |
Remarks |
- |
Keywords |
cation transporter; substrate selectivity; alanine mutants; PMAT activity; Helical wheel analysis |